Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12148666 | 0.78 | TSHR (0.41) | SMN1; SMN2TSHRLMNAMEN1KMT2A | |
| SCHEMBL1146035 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL23478964 | 0.77 | GABRP (0.48) | SMN1; SMN2GABRA1GABRA5RAB9A | |
| SCHEMBL30185830 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL27876174 | 0.77 | CYP11B1 (0.42) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20749289 | 0.77 | TSHR (0.55) | SMN1; SMN2TSHRLMNAMEN1KMT2A | |
| SCHEMBL13954333 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRLMNAMEN1KMT2A | |
| SCHEMBL12147850 | 0.76 | TSHR (0.41) | SMN1; SMN2TSHRLMNAMEN1KMT2A | |
| SCHEMBL12336888 | 0.75 | HRH3 (0.40) | SMN1; SMN2LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL24448 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-9012654-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)-alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2015-04-21 | — | — | US | disclosed |
| US-20150080432-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-8912222-B2 | Method to control insects resistant to common insecticides | DOW AGROSCIENCES, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140315840-A1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | CORTEVA AGRISCIENCE LLC | 2014-10-23 | — | — | US | disclosed |
| US-8846717-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES, LLC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20140135362-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2014-05-15 | — | — | US | disclosed |
| US-8669278-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | DOW AGROSCIENCES, LLC. (US) | 2014-03-11 | — | — | US | disclosed |
| US-20130288897-A1 | SYNERGISTIC PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-10-31 | — | — | US | disclosed |
| US-8513462-B2 | Pesticides and uses thereof | DOW AGROSCIENCES LLC (US) | 2013-08-20 | — | — | US | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20120316067-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2012-12-13 | — | — | US | disclosed |
| US-20120231953-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2012-09-13 | — | — | US | disclosed |
| US-20120135866-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (US) | 2012-05-31 | — | — | US | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110200684-A1 | SYNERGISTIC PESTICIDAL MIXTURES | DOW AGROSCIENCES LLC (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110196001-A1 | METHOD TO CONTROL INSECTS RESISTANT TO COMMON INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2011-08-11 | — | — | US | disclosed |
| WO-2010089993-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | クミアイ化学工業株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316067-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | PRDX6, DDT, HDHD5 | SMN1; SMN2 1544/4885TSHR 1246/4885LMNA 4513/4885 |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | SMN1; SMN2 2712/4885TSHR 635/4885LMNA 3308/4885 |
| US-20140315840-A1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | DDT, AGPS, SMOX | SMN1; SMN2 938/4885TSHR 3723/4885LMNA 3793/4885 |
| US-20120135866-A1 | INCREASING PLANT VIGOR | HDLBP, VPS4B, VPS28 | SMN1; SMN2 2152/4885TSHR 3665/4885LMNA 4449/4885 |
| US-20150080432-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | NPEPPS, HDHD5, PRDX6 | SMN1; SMN2 1880/4885TSHR 1586/4885LMNA 4473/4885 |
| US-20120231953-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | NPEPPS, PRDX6, HDHD5 | SMN1; SMN2 1681/4885TSHR 1939/4885LMNA 4514/4885 |
| US-20110200684-A1 | SYNERGISTIC PESTICIDAL MIXTURES | ACHE, DDT, PDE1C | SMN1; SMN2 2705/4885TSHR 1142/4885LMNA 4435/4885 |
| US-20130288897-A1 | SYNERGISTIC PESTICIDAL COMPOSITIONS | DDT, ACHE, DPP3 | SMN1; SMN2 3036/4885TSHR 1966/4885LMNA 4635/4885 |
| US-20110196001-A1 | METHOD TO CONTROL INSECTS RESISTANT TO COMMON INSECTICIDES | DDT, GSS, AS3MT | SMN1; SMN2 1191/4885TSHR 1583/4885LMNA 3993/4885 |
| US-20140135362-A1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)-ALKYL SULFOXIMINES | NPEPPS, HDHD5, PRDX6 | SMN1; SMN2 1880/4885TSHR 1586/4885LMNA 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.