Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202029 | 0.80 | RIPK1 (0.33) | ALOX5APFEN1PARP15PARP10BRD4 | |
| SCHEMBL20204679 | 0.80 | BRD4 (0.33) | ALOX5APFEN1PARP15PARP10BRD4 | |
| SCHEMBL20374442 | 0.68 | PARP10 (0.45) | PARP15PARP10 | |
| SCHEMBL24180121 | 0.68 | ALOX5AP (0.34) | ALOX5APFEN1 | |
| SCHEMBL24224650 | 0.68 | RIPK1 (0.36) | ALOX5APFEN1 | |
| SCHEMBL20376461 | 0.66 | CYP1A2 (0.38) | ALOX5APFEN1BRD4 | |
| SCHEMBL20201618 | 0.66 | ALOX5AP (0.36) | ALOX5APFEN1 | |
| SCHEMBL21736840 | 0.65 | PARP10 (0.48) | PARP15PARP10 | |
| SCHEMBL16522856 | 0.65 | GPR84 (0.53) | PARP14 | |
| SCHEMBL29037151 | 0.64 | AXL (0.36) | ALOX5APFEN1PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |