Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217728 | 0.84 | P2RX7 (0.46) | L3MBTL1GAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20217503 | 0.83 | L3MBTL1 (0.46) | L3MBTL1GAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16308804 | 0.78 | CYP3A4 (0.57) | L3MBTL1GAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16296527 | 0.78 | CYP3A4 (0.57) | L3MBTL1GAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16296529 | 0.78 | CYP3A4 (0.57) | L3MBTL1GAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20211273 | 0.78 | CYP3A4 (0.57) | L3MBTL1GAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20217341 | 0.77 | CYP3A4 (0.40) | ALDH1A1LMNACYP3A4RAB9A | |
| SCHEMBL20217804 | 0.77 | RAB9A (0.43) | L3MBTL1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL20217473 | 0.74 | MAPT (0.40) | L3MBTL1GAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL20217636 | 0.74 | NAMPT (0.39) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |