Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.35 |
| ▸ | F7 | P08709 | 3/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 4/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217678 | 0.75 | ALDH1A1 (0.38) | F7S1PR2S1PR4S1PR3ALDH1A1 | |
| SCHEMBL20217652 | 0.75 | TAS1R3 (0.40) | TAS1R3TAS1R1F7F3S1PR2 | |
| SCHEMBL20217171 | 0.70 | CYP3A4 (0.43) | TAS1R3TAS1R1F7F3S1PR2 | |
| SCHEMBL20217231 | 0.70 | CYP3A4 (0.43) | TAS1R3TAS1R1F7F3S1PR2 | |
| SCHEMBL20217664 | 0.70 | CYP3A4 (0.47) | ALDH1A1 | |
| SCHEMBL20217358 | 0.70 | ACACB (0.38) | ALDH1A1LNPEP | |
| SCHEMBL20217478 | 0.68 | LMNA (0.42) | ALDH1A1 | |
| SCHEMBL20217669 | 0.67 | MEN1 (0.40) | TAS1R3TAS1R1ALDH1A1F10 | |
| SCHEMBL20217428 | 0.67 | CYP3A4 (0.41) | F7 | |
| SCHEMBL20217912 | 0.66 | CYP3A4 (0.43) | S1PR2S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |