Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217341 | 0.78 | CYP3A4 (0.40) | CYP3A4TTKAURKBINCENPSMYD3 | |
| SCHEMBL20217636 | 0.76 | NAMPT (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL20217804 | 0.76 | RAB9A (0.43) | CYP3A4TTKAURKBINCENPNPC1 | |
| SCHEMBL20217529 | 0.72 | L3MBTL1 (0.45) | CYP3A4RAB9A | |
| SCHEMBL20217764 | 0.69 | CYP3A4 (0.49) | CYP3A4TTKAURKBINCENPF2 | |
| SCHEMBL20217496 | 0.67 | CYP3A4 (0.62) | CYP3A4TTKAURKBINCENPF2 | |
| SCHEMBL20217662 | 0.67 | CYP3A4 (0.47) | CYP3A4TTKAURKBINCENPSMYD3 | |
| SCHEMBL20217579 | 0.67 | CYP3A4 (0.65) | CYP3A4TTKAURKBINCENP | |
| SCHEMBL20217956 | 0.67 | CYP3A4 (0.48) | CYP3A4TTKAURKBINCENPSMYD3 | |
| SCHEMBL20217623 | 0.67 | HPGD (0.45) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |