Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15470068 | 0.88 | L3MBTL1 (0.45) | S1PR4CRHR1MAPTHTTALDH1A1 | |
| SCHEMBL20219489 | 0.84 | TLR8 (0.44) | CRHR1MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL20219408 | 0.81 | TLR8 (0.42) | L3MBTL1 | |
| SCHEMBL13195680 | 0.81 | FLT3 (0.41) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20219647 | 0.81 | F2 (0.36) | STK17A | |
| SCHEMBL23472630 | 0.80 | MAPT (0.39) | MAPTHTTALDH1A1HPGDCYP1A2 | |
| SCHEMBL20219401 | 0.79 | ALDH1A1 (0.43) | HTTALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL20219406 | 0.79 | S1PR4 (0.35) | S1PR4TDP1MAPTHTTALDH1A1 | |
| SCHEMBL23472210 | 0.79 | MTNR1B (0.47) | MAPT | |
| SCHEMBL23472201 | 0.78 | TLR7 (0.51) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |