Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | FURIN | P09958 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21898136 | 0.83 | FURIN (0.36) | AKT1FAPMMP1MMP3MMP9 | |
| SCHEMBL19619238 | 0.80 | FAP (0.40) | FAPFURIN | |
| SCHEMBL20029727 | 0.77 | FURIN (0.35) | MMP1MMP3MMP9FURIN | |
| SCHEMBL21297140 | 0.76 | FAP (0.35) | FAPFURIN | |
| SCHEMBL25787322 | 0.76 | FAP (0.35) | FAPFURIN | |
| SCHEMBL21297079 | 0.76 | FAP (0.35) | FAPFURIN | |
| SCHEMBL21297142 | 0.76 | FAP (0.35) | FAPFURIN | |
| SCHEMBL19170785 | 0.75 | SIRT5 (0.33) | AKT1FAPFURIN | |
| SCHEMBL20340684 | 0.75 | FAP (0.37) | FAPFURIN | |
| SCHEMBL18824125 | 0.75 | SMN1; SMN2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180154011-A1 | SELF-STABILIZING LINKER CONJUGATES | SEAGEN INC. | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180154011-A1 | SELF-STABILIZING LINKER CONJUGATES | BCR, CD44, FOLR1 | AKT1 4002/4885FAP 2052/4885MMP1 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.