Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 7/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | NPY4R | P50391 | 3/20 | 0.30 |
| ▸ | NPY1R | P25929 | 2/20 | 0.30 |
| ▸ | NPY2R | P49146 | 2/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19619238 | 0.86 | FAP (0.40) | FURINFAPNPY4RNPY1RNPY2R | |
| SCHEMBL20029727 | 0.85 | FURIN (0.35) | FURINC3AR1MMP1MMP3MMP9 | |
| SCHEMBL13805702 | 0.84 | FURIN (0.32) | FURINC3AR1FAPPOLBOPRK1 | |
| SCHEMBL21297079 | 0.83 | FAP (0.35) | FURINC3AR1FAPNPY4RNPY1R | |
| SCHEMBL21297142 | 0.83 | FAP (0.35) | FURINC3AR1FAPNPY4RNPY1R | |
| SCHEMBL21297140 | 0.83 | FAP (0.35) | FURINC3AR1FAPNPY4RNPY1R | |
| SCHEMBL20222905 | 0.83 | AKT1 (0.31) | FURINAKT1MMP1MMP3MMP9 | |
| SCHEMBL25787322 | 0.83 | FAP (0.35) | FURINC3AR1FAPNPY4RNPY1R | |
| SCHEMBL23106157 | 0.82 | FURIN (0.39) | FURINAKT1LMNAOPRM1OPRD1 | |
| SCHEMBL15870228 | 0.81 | FAP (0.34) | FURINFAPOPRK1NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135723-A1 | ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | ABBVIE INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20200121803-A1 | ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | ABBVIE INC. | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135723-A1 | ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | CD99, SLC3A2, CD63 | FURIN 4666/4885AKT1 4573/4885C3AR1 2936/4885 |
| US-20200121803-A1 | ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | CD99, SLC3A2, CD63 | FURIN 4666/4885AKT1 4573/4885C3AR1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.