Bicarbonate

Bicarbonate

SCHEMBL2023099

O.O.O.O.O=C([O-])O.[Ni+2].[OH-]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA4 P22748 5/20 0.39
CA1 P00915 3/20 0.39
FAHD1 Q6P587 1/20 0.39
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.31
LDHA P00338 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
ACHE P22303 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL9950136 1.00
Bicarbonate SCHEMBL2028638 0.95 CA4 (0.42) CA4CA1FAHD1CA2CA9
Bicarbonate SCHEMBL472827 0.95
Bicarbonate SCHEMBL16225125 0.91 CA4 (0.43) CA4CA1FAHD1CA2CA9
Bicarbonate SCHEMBL2454268 0.90
Bicarbonate SCHEMBL570557 0.90
Bicarbonate SCHEMBL873152 0.90 CA4 (0.39) CA4CA1FAHD1CA2CA9
Bicarbonate SCHEMBL21734207 0.90
Bicarbonate SCHEMBL21638664 0.90 CA4 (0.39) CA4CA1FAHD1CA2CA9
Bicarbonate SCHEMBL28853718 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262128-A Method for forming aryl carbon-nitrogen bond by illumination and photoreactor for carrying out the reaction 科罗拉多州立大学研究基金会 2021-01-22 CN claimed
US-20200147581-A1 METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2020-05-14 US claimed
US-20190345122-A1 METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2019-11-14 US claimed
US-20170271637-A1 METHOD OF MANUFACTURING POROUS POLYMER MEMBRANE USING WATER PRESSURE AND BATTERY SEPARATOR COMPRISING POROUS POLYMER MEMBRANE MANUFACTURED BY THE METHOD SANGMYUNG UNIVERSITY SEOUL INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2017-09-21 US claimed
WO-2007140525-A1 A METHOD OF TREATMENT AND PROPHYLAXIS OF EVENTS, CONDITIONS AND DISEASES OF THE SYSTEMIC VASCULATURE AN IMMUNE FUNCTION TO DECREASE CARDIOVASCULAR RISK AND PATHOGENIC INFECTION HOENIG MICHEL (AU) 2007-12-13 WO claimed
US-20250257315-A1 CARBO-IONIC CULTURES AND EXTRACTS AND APPLICATIONS THEREOF Bio Capital Holdings, LLC 2025-08-14 US disclosed
US-12270023-B2 Carbo-ionic cultures and extracts and applications thereof Bio Capital Holdings, LLC (US) 2025-04-08 US disclosed
US-RE50296-E1 Electron beam resist composition THE UNIVERSITY OF MANCHESTER (GB) 2025-02-11 US disclosed
US-20220169607-A1 CARBAZOLE AND ACRIDINE PHOTOREDOX CATALYSTS FOR SMALL MOLECULE AND MACROMOLECULAR TRANSFORMATIONS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2022-06-02 US disclosed
US-20220145240-A1 CARBO-IONIC CULTURES AND EXTRACTS AND APPLICATIONS THEREOF BIOCAPITAL HOLDINGS, LLC 2022-05-12 US disclosed
US-11316146-B2 Redox and ion-adsorption electrodes and energy storage devices THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-26 US disclosed
CN-113376958-A Electron beam resist composition 曼彻斯特大学 2021-09-10 CN disclosed
US-20080137316-A1 CONDUCTIVE PATTERNS AND METHODS OF USING THEM CITIBANK, N.A. 2008-06-12 US disclosed
WO-2008036752-A2 SOLVENT SYSTEMS FOR METALS AND INKS FRY'S METALS, INC. (US) 2008-03-27 WO disclosed
WO-2008017062-A1 PARTICLES AND INKS AND FILMS USING THEM FRY'S METALS, INC. (US) 2008-02-07 WO disclosed
US-20080032047-A1 PARTICLES AND INKS AND FILMS USING THEM CITIBANK, N.A. 2008-02-07 US disclosed
WO-2007140525-A1 A METHOD OF TREATMENT AND PROPHYLAXIS OF EVENTS, CONDITIONS AND DISEASES OF THE SYSTEMIC VASCULATURE AN IMMUNE FUNCTION TO DECREASE CARDIOVASCULAR RISK AND PATHOGENIC INFECTION HOENIG MICHEL (AU) 2007-12-13 WO disclosed
US-6693154-B2 AN ORGANOMETALLIC COMPLEX CONTAINS A TRANSITION OR LANTHANIDE METAL AND 1,3-BIS(ARYLIMINO)ISOINDOLINE OR 1,3-BIS(HETEROARYLIMINO) ISOINDOLINE; ETHYLENE COPOLYMER WITH HIGH MOLECULAR WEIGHT, BROAD MOLECULAR WEIGHT DISTRIBUTION EQUISTAR CHEMICALS, LP 2004-02-17 US disclosed
US-20030065113-A1 Transition metal catalysts for olefin polymerization EQUISTAR CHEMICALS, LP 2003-04-03 US disclosed
US-6383975-B1 CATALYTIC HYDROTREATMENT OF MIDDLE AND HEAVY OILS, IMPREGNATION OF GROUP IVB METAL ON ALUMINA, DRYING AND ROASTING IMPREGNATION OF THE ALUMINA WITH A TI COMPOUND, SOLUBLE IN AN ORGANIC SOLVENT, INSTITUTO MEXICANO DEL PETROLEO (MX) 2002-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220169607-A1 CARBAZOLE AND ACRIDINE PHOTOREDOX CATALYSTS FOR SMALL MOLECULE AND MACROMOLECULAR TRANSFORMATIONS PCNA, PPOX, PARP1 CA4 1388/4885CA1 3909/4885FAHD1 4227/4885
US-20190345122-A1 METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS TYR, CRY2, CRY1 CA4 205/4885CA1 356/4885FAHD1 4868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.