SCHEMBL20235169

SCHEMBL20235169

CC(=O)NC1C(C(C)C)OC(CO)C(O)C1OC1OC(C(=O)O)C(OC(C)C)C(O)C1O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.49
▸ ALDH1A1 P00352 2/20 0.45
▸ THRB P10828 1/20 0.45
▸ LGALS3 P17931 3/20 0.42
▸ LGALS8 O00214 1/20 0.42
▸ LGALS4 P56470 1/20 0.42
▸ MDK P21741 3/20 0.41
▸ BDNF P23560 3/20 0.41
▸ PTN P21246 2/20 0.41
▸ CD69 Q07108 1/20 0.40
▸ MAG P20916 1/20 0.39
▸ NOD2 Q9HC29 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ CHIA Q9BZP6 1/20 0.36
▸ SELL P14151 1/20 0.36
▸ SELP P16109 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26473755 0.92 ALDH1A1 (0.47) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL19546052 0.91 MAPK1 (0.47) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL26471213 0.90 BDNF (0.44) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL21695250 0.89 MAPK1 (0.50) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL26471206 0.88 MAPK1 (0.43) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL14089004 0.87 MAPK1 (0.57) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL13246090 0.87 MAPK1 (0.47) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL26471263 0.87 MAPK1 (0.46) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL17742330 0.85 ALDH1A1 (0.53) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL25964185 0.85 MAPK1 (0.45) MAPK1ALDH1A1THRBLGALS3LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230133656-A1 HYDROGEL COMPOSITIONS AND USES THEREOF SHOICHET, MOLLY SANDRA (CA) 2023-05-04 — — US disclosed
US-20230133656-A1 HYDROGEL COMPOSITIONS AND USES THEREOF SHOICHET, MOLLY SANDRA (CA) 2023-05-04 — — US disclosed
US-10806797-B2 Prodrugs comprising an GLP-1/glucagon dual agonist linker hyaluronic acid conjugate SANOFI (FR) 2020-10-20 — — US disclosed
US-10792367-B2 Conjugates comprising an GLP-1/glucagon dual agonist, a linker and hyaluronic acid SANOFI (FR) 2020-10-06 — — US disclosed
US-20180154005-A1 CONJUGATES COMPRISING AN GLP-1/GLUCAGON DUAL AGONIST, A LINKER AND HYALURONIC ACID SANOFI (FR) 2018-06-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133656-A1 HYDROGEL COMPOSITIONS AND USES THEREOF CD44, UACA, ALDH1A2 MAPK1 3667/4885ALDH1A1 160/4885THRB 1840/4885
US-10792367-B2 Conjugates comprising an GLP-1/glucagon dual agonist, a linker and hyaluronic acid GLP1R, GIPR, GCGR MAPK1 268/4885ALDH1A1 934/4885THRB 183/4885
US-10806797-B2 Prodrugs comprising an GLP-1/glucagon dual agonist linker hyaluronic acid conjugate GLP1R, GIPR, GHSR MAPK1 289/4885ALDH1A1 988/4885THRB 229/4885
US-20180154005-A1 CONJUGATES COMPRISING AN GLP-1/GLUCAGON DUAL AGONIST, A LINKER AND HYALURONIC ACID GLP1R, GIPR, GCGR MAPK1 300/4885ALDH1A1 1081/4885THRB 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback