Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 5/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10207144 | 1.00 | BCL2 (0.31) | BCL2OPRM1OPRD1ROCK1 | |
| SCHEMBL895538 | 0.84 | DRD2 (0.32) | — | |
| SCHEMBL895541 | 0.84 | DRD2 (0.32) | — | |
| SCHEMBL895540 | 0.84 | DRD2 (0.32) | — | |
| SCHEMBL895357 | 0.79 | OPRM1 (0.33) | OPRM1OPRD1 | |
| SCHEMBL895373 | 0.74 | OPRD1 (0.40) | OPRM1OPRD1 | |
| SCHEMBL20243398 | 0.70 | — | — | |
| SCHEMBL10207152 | 0.69 | THRB (0.32) | — | |
| SCHEMBL896033 | 0.69 | PNMT (0.31) | — | |
| SCHEMBL10207328 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994594-B2 | Inhibitors of arginase and their therapeutic applications | MARS, INCORPORATED (US) | 2018-06-12 | — | — | US | disclosed |