Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20245492 | 0.77 | OPRM1 (0.42) | ACHEELANEOPRM1OPRD1 | |
| SCHEMBL20245632 | 0.70 | ACHE (0.47) | ACHEOPRM1OPRD1 | |
| SCHEMBL19896474 | 0.69 | FAAH (0.43) | DRD2ADRA1A | |
| SCHEMBL17304236 | 0.68 | ALK (0.33) | — | |
| SCHEMBL20245630 | 0.67 | OPRM1 (0.46) | ACHEELANEOPRM1OPRD1 | |
| SCHEMBL9549940 | 0.66 | ACHE (0.42) | ACHEOPRM1OPRD1 | |
| SCHEMBL9619687 | 0.66 | ELANE (0.53) | ACHEDRD2DRD3ELANEADRA1A | |
| SCHEMBL26785760 | 0.66 | ALDH1A1 (0.43) | — | |
| SCHEMBL17304238 | 0.64 | ALK (0.33) | SSTR4 | |
| SCHEMBL14775521 | 0.64 | PTGDR2 (0.46) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3333156-A2 | BENZOMORPHAN ANALOGS AND THE USE THEREOF | Purdue Pharma L.P. (US) | 2018-06-13 | — | — | EP | disclosed |