Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20248916 | 0.86 | ALDH1A1 (0.69) | MAPTALDH1A1GAAHPGDKDM4E | |
| SCHEMBL20254573 | 0.86 | MAPT (0.67) | MAPTALDH1A1GAAHPGDKDM4E | |
| SCHEMBL20248920 | 0.80 | MEN1 (0.63) | MAPTALDH1A1GAAHPGDKDM4E | |
| SCHEMBL20248931 | 0.77 | MAPT (0.43) | MAPTALDH1A1GAAHPGDMEN1 | |
| Dimethylamine SCHEMBL9706176 | 0.76 | MAPT (0.67) | MAPTALDH1A1GAAHPGDKDM4E | |
| SCHEMBL20248958 | 0.76 | MAPK1 (0.78) | MAPTALDH1A1GAAHPGDMEN1 | |
| SCHEMBL1611235 | 0.73 | KDM4E (0.52) | MAPTALDH1A1GAAHPGDKDM4E | |
| SCHEMBL20248923 | 0.71 | ALDH1A1 (0.52) | MAPTALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL20254403 | 0.70 | ALDH1A1 (0.67) | MAPTALDH1A1GAAHPGDKDM4E | |
| Dimethylamine SCHEMBL9706158 | 0.69 | MAPT (0.60) | MAPTALDH1A1GAAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180162867-A1 | EIS INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162867-A1 | EIS INHIBITORS | EP300, ACAT1, ACAT2 | MAPT 4313/4885ALDH1A1 1232/4885GAA 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.