SCHEMBL202585

SCHEMBL202585

CC(C)(C)CC(C)(C)Sc1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.40
PTPN1 P18031 4/20 0.39
PTPN6 P29350 2/20 0.39
PTPN2 P17706 1/20 0.39
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
PDE4B Q07343 2/20 0.36
SLC22A12 Q96S37 1/20 0.35
ESR2 Q92731 1/20 0.34
ALOX5 P09917 1/20 0.33
HNF4A P41235 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
HPN P05981 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
SIRT5 Q9NXA8 1/20 0.33
HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202583 0.84 SLC22A12 (0.35) SLC22A12
SCHEMBL199944 0.82 BACE1 (0.45) BACE1PTPN1PTPN6PTPN2AKR1C3
SCHEMBL199860 0.76 SHBG (0.47) BACE1PTPN1PTPN6PTPN2PDE4B
SCHEMBL10351871 0.75 ALDH1A1 (0.37) PTPN1MAPTALDH1A1HPGDHSD17B10
Barium SCHEMBL2729092 0.74 ALDH1A1 (0.36) PTPN1MAPTALDH1A1HPGDHSD17B10
SCHEMBL201240 0.73 ESR1 (0.39) ESR2HPNMAPTALOX15SIRT5
SCHEMBL201152 0.70 GABRA1 (0.41) ESR2HPNMAPTALOX15SIRT5
SCHEMBL201826 0.69 CA1 (0.48) HPNMAPTALOX15SIRT5HPGD
SCHEMBL200188 0.69 BACE1 (0.49) BACE1PTPN1PDE4BESR2ALOX5
SCHEMBL296464 0.69 BACE1 (0.49) BACE1PTPN1AKR1C3AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10230023-B2 Color converter BASF SE (DE) 2019-03-12 US disclosed
EP-2718395-B1 Novel illumination device comprising a colour converter BASF SE (DE) 2018-02-28 EP disclosed
US-20160284947-A1 NOVEL COLOR CONVERTER BASF SE (DE) 2016-09-29 US disclosed
US-9406848-B2 Color converter BASF SE (DE) 2016-08-02 US disclosed
EP-2718395-A1 NOVEL COLOR CONVERTER BASF SE (DE) 2014-04-16 EP disclosed
US-8501948-B2 Multiple chromophores based on rylene BASF AKTIENGESELLSCHAFT (DE) 2013-08-06 US disclosed
WO-2012168395-A1 NOVEL COLOR CONVERTER BASF SE (DE) 2012-12-13 WO disclosed
US-20120138125-A1 FLUORESCENT SOLAR CONVERSION CELLS BASED ON FLUORESCENT TERYLENE DYES BASF SE (DE) 2012-06-07 US disclosed
US-8088922-B2 Dibenzorylenetetracarboximides as infrared absorbers BASF AKTIENGESELLSCHAFT (DE) 2012-01-03 US disclosed
US-8071775-B2 photovoltaics; emitters in chemiluminescence applications; field-effect transistors and electrophotography; N,N'-Bis(2,6-diisopropylphenyl)-1,7- and -1,6-bis(2,6-diisopropylphenoxy)-perylene-3,4:9,10-tetracarboximide BASF AKTIENGESELLSCHAFT (DE) 2011-12-06 US disclosed
US-20100048904-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF AKTIENGESELLSCHAFT (DE) 2010-02-25 US disclosed
US-20080287678-A1 Multiple Chromophores Based on Rylene BASF AKTIENGESELLSCHAFT (DE) 2008-11-20 US disclosed
US-20080245411-A1 Fluorescent Solar Conversion Cells Based on Fluorescent Terylene Dyes BASF SE 2008-10-09 US disclosed
US-20080167467-A1 Substituted Rylene Derivatives BASF AKTIENGESELLSCHAFT (DE) 2008-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167467-A1 Substituted Rylene Derivatives NR3C2, NR2C2, NR2E3 BACE1 4387/4885PTPN1 760/4885PTPN6 904/4885
US-20100048904-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS TDO2, C9, CYP3A43 BACE1 1904/4885PTPN1 4788/4885PTPN6 4807/4885
US-20080287678-A1 Multiple Chromophores Based on Rylene TDO2, PPOX, NPY1R BACE1 4681/4885PTPN1 1417/4885PTPN6 1799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.