Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29372134 | 1.00 | GAA (0.45) | GAAPLA2G1BATG4BKMT2AMAPT | |
| SCHEMBL7797904 | 0.82 | PLA2G1B (0.44) | PLA2G1BATG4BKMT2AMAPTALDH1A1 | |
| SCHEMBL2022034 | 0.81 | ALDH1A1 (0.50) | GAAPLA2G1BATG4BKMT2AMAPT | |
| SCHEMBL15908528 | 0.79 | L3MBTL1 (0.40) | GAAPLA2G1BATG4BKMT2AMAPT | |
| SCHEMBL12491645 | 0.77 | KMT2A (0.38) | GAAPLA2G1BATG4BKMT2AMAPT | |
| SCHEMBL28101463 | 0.77 | GAA (0.58) | GAAKMT2AMAPTALOX12ALDH1A1 | |
| SCHEMBL20472487 | 0.76 | P2RX7 (0.43) | KMT2AALDH1A1 | |
| SCHEMBL29375481 | 0.75 | CTSL (0.34) | GAAPLA2G1BATG4BKMT2AMAPT | |
| SCHEMBL13537180 | 0.74 | MTNR1A (0.43) | KMT2A | |
| SCHEMBL2206871 | 0.74 | ALDH1A1 (0.38) | GAAKMT2AMAPTALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115246817-B | Crystal form beta of compound A benzoate, preparation method thereof and pharmaceutical composition containing crystal form beta | 深圳信立泰药业股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113493435-B | Amorphous compound A benzoate, preparation method thereof and pharmaceutical composition containing amorphous compound A benzoate | 深圳信立泰药业股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-115246817-A | Crystal form beta of compound A benzoate, preparation method thereof and pharmaceutical composition containing crystal form | 深圳信立泰药业股份有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-106349215-B | Amorphous form of compound A benzoate, preparation method thereof and pharmaceutical composition containing amorphous form | 深圳信立泰药业股份有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-104803971-B | Crystal form alpha of compound A mono benzoate, preparation method thereof and pharmaceutical composition containing crystal form | 深圳信立泰药业股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-113493435-A | Amorphous form of compound A benzoate, preparation method thereof and pharmaceutical composition containing amorphous form | 深圳信立泰药业股份有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-106349216-B | Crystal form alpha of compound A, preparation method thereof and pharmaceutical composition containing crystal form | 深圳信立泰药业股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-9340523-B2 | Certain dipeptidyl peptidase inhibitors | FOCHON PHARMA, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9340523-B2 | Certain dipeptidyl peptidase inhibitors | FOCHON PHARMA, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| EP-2521721-B1 | 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2014-10-01 | — | — | EP | disclosed |
| EP-2521721-B1 | 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2014-10-01 | — | — | EP | disclosed |
| US-20140213590-A1 | CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS | FOCHON PHARMA, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-20140213590-A1 | CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS | FOCHON PHARMA, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-8648073-B2 | Certain dipeptidyl peptidase inhibitors | FOCHON PHARMA, INC. (US) | 2014-02-11 | — | — | US | disclosed |
| US-8648073-B2 | Certain dipeptidyl peptidase inhibitors | FOCHON PHARMA, INC. (US) | 2014-02-11 | — | — | US | disclosed |
| EP-2521721-A1 | 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS | Shanghai Fochon Pharmaceutical Co. Ltd (CN) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011079778-A1 | 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS | CHINA SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011079778-A1 | 3-(3-AMINOPIPERIDIN-1-YL)-5-OXO-1,2,4-TRIAZINE DERIVATES AS DIPEPTIDYL PEPTIDASE IV(DPP-IV) INHIBITORS | CHINA SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2011-07-07 | — | — | WO | disclosed |
| US-20110160212-A1 | CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS | FOCHON PHARMA, INC. | 2011-06-30 | — | — | US | disclosed |
| US-20110160212-A1 | CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS | FOCHON PHARMA, INC. | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160212-A1 | CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS | DPP4, DPP3, DPP8 | GAA 97/4885PLA2G1B 2045/4885ATG4B 205/4885 |
| US-20140213590-A1 | CERTAIN DIPEPTIDYL PEPTIDASE INHIBITORS | DPP4, DPP3, DPP8 | GAA 97/4885PLA2G1B 2045/4885ATG4B 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.