Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MDH1 | P40925 | 1/20 | 0.40 |
| ▸ | MDH2 | P40926 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274176 | 0.92 | MCHR1 (0.49) | FAAHL3MBTL1MCHR1SCN9A | |
| SCHEMBL20274158 | 0.81 | LTA4H (0.53) | FAAHL3MBTL1MCHR1MDH1MDH2 | |
| SCHEMBL20274177 | 0.79 | AKR1B1 (0.48) | L3MBTL1SIGMAR1MDH1MDH2SCN9A | |
| SCHEMBL20274125 | 0.79 | AKR1B1 (0.53) | L3MBTL1 | |
| SCHEMBL20274135 | 0.77 | FAAH (0.47) | FAAH | |
| SCHEMBL20274133 | 0.74 | MAOA (0.51) | FAAHL3MBTL1SIGMAR1MDH1MDH2 | |
| SCHEMBL20274112 | 0.73 | HRH3 (0.60) | MCHR1SCN9A | |
| SCHEMBL15707895 | 0.73 | AR (0.39) | FAAHMCHR1CXCR3 | |
| SCHEMBL15727605 | 0.73 | AR (0.39) | FAAHMCHR1CXCR3 | |
| SCHEMBL6755108 | 0.72 | MAOA (0.51) | FAAHMCHR1SIGMAR1CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |