Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274138 | 0.92 | FAAH (0.46) | MCHR1FAAHSCN9AL3MBTL1 | |
| SCHEMBL6755108 | 0.81 | MAOA (0.51) | MCHR1FAAHHTR2CMAPT | |
| SCHEMBL20274112 | 0.81 | HRH3 (0.60) | MCHR1SCN9ASCN7AKCNH2MAPT | |
| SCHEMBL20274158 | 0.80 | LTA4H (0.53) | MCHR1FAAHL3MBTL1HTR2CLTA4H | |
| SCHEMBL6754196 | 0.78 | MCHR1 (0.57) | MCHR1MAPT | |
| SCHEMBL20274135 | 0.76 | FAAH (0.47) | FAAHKCNH2 | |
| SCHEMBL6752995 | 0.76 | MCHR1 (0.47) | MCHR1HTR2CMAPT | |
| SCHEMBL20274125 | 0.76 | AKR1B1 (0.53) | L3MBTL1 | |
| SCHEMBL20274177 | 0.76 | AKR1B1 (0.48) | SCN9AL3MBTL1KCNH2PDE3BPDE3A | |
| SCHEMBL20274133 | 0.75 | MAOA (0.51) | FAAHL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |