Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 8/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274215 | 0.79 | PIM1 (0.43) | HRH3L3MBTL1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL20274170 | 0.78 | L3MBTL1 (0.44) | L3MBTL1PIM1 | |
| SCHEMBL15727726 | 0.76 | AR (0.36) | L3MBTL1MC4R | |
| SCHEMBL15727730 | 0.75 | STAT3 (0.34) | MC4RPIM1 | |
| SCHEMBL15750158 | 0.73 | PIM1 (0.41) | HRH3L3MBTL1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL20274189 | 0.72 | L3MBTL1 (0.44) | HRH3L3MBTL1 | |
| SCHEMBL20274131 | 0.69 | HRH4 (0.48) | HRH3L3MBTL1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL20274202 | 0.69 | AKR1B1 (0.50) | HRH3L3MBTL1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL23335840 | 0.68 | PIM1 (0.56) | HRH3PIM1 | |
| SCHEMBL20274172 | 0.67 | POLB (0.38) | HRH3CACNA2D1CACNA1BCACNB1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |