Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MDH1 | P40925 | 1/20 | 0.40 |
| ▸ | MDH2 | P40926 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274170 | 0.87 | L3MBTL1 (0.44) | L3MBTL1MDH1MDH2MEN1KMT2A | |
| SCHEMBL20274133 | 0.77 | MAOA (0.51) | L3MBTL1MDH1MDH2MAOASIGMAR1 | |
| SCHEMBL20274177 | 0.75 | AKR1B1 (0.48) | L3MBTL1MDH1MDH2MEN1KMT2A | |
| SCHEMBL15727607 | 0.75 | MAPK1 (0.37) | ALDH1A1 | |
| SCHEMBL20274213 | 0.73 | MAOA (0.47) | L3MBTL1MAOAHRH3 | |
| SCHEMBL20274136 | 0.73 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL20274144 | 0.72 | MDH1 (0.38) | L3MBTL1MDH1MDH2MEN1KMT2A | |
| SCHEMBL20274200 | 0.72 | HRH3 (0.40) | L3MBTL1HRH3 | |
| SCHEMBL20274140 | 0.72 | ALDH1A1 (0.48) | KMT2AKDM4EALDH1A1TBXAS1TP53 | |
| SCHEMBL20274192 | 0.72 | HRH3 (0.45) | L3MBTL1MDH1MDH2MAOASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |