Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16310260 | 0.92 | TDP1 (0.45) | ALDH1A1TDP1TSHRGPR35LMNA | |
| SCHEMBL13098118 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRGPR35LMNA | |
| SCHEMBL1167739 | 0.88 | TSHR (0.53) | ALDH1A1TDP1TSHRGPR35HPGD | |
| SCHEMBL962484 | 0.86 | MGMT (0.40) | ALDH1A1TDP1TSHRGPR35LMNA | |
| SCHEMBL68734 | 0.86 | MAPT (0.41) | ALDH1A1TDP1TSHRLMNACYP3A4 | |
| SCHEMBL66337 | 0.86 | TDP1 (0.64) | ALDH1A1TDP1TSHRCYP3A4HPGD | |
| SCHEMBL27962021 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRGPR35LMNA | |
| SCHEMBL5281894 | 0.86 | GPR35 (0.56) | ALDH1A1TDP1TSHRGPR35S100A4 | |
| SCHEMBL6655415 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRGPR35LMNA | |
| SCHEMBL6967217 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217063-B1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | VIRGINIA TECH INTELL PROP (US) | 2014-12-17 | — | — | EP | disclosed |
| EP-2217063-B1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | VIRGINIA TECH INTELL PROP (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8558019-B2 | Thiolated paclitaxels for reaction with gold nanoparticles as drug delivery agents | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-8558019-B2 | Thiolated paclitaxels for reaction with gold nanoparticles as drug delivery agents | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-8558019-B2 | Thiolated paclitaxels for reaction with gold nanoparticles as drug delivery agents | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20110144163-A1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | ZAHAV BIOSCIENCES LLC | 2011-06-16 | — | — | US | disclosed |
| US-20110144163-A1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | ZAHAV BIOSCIENCES LLC | 2011-06-16 | — | — | US | disclosed |
| US-20110144163-A1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | ZAHAV BIOSCIENCES LLC | 2011-06-16 | — | — | US | disclosed |
| WO-2009062138-A1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144163-A1 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS | TUBB6, TUBB1, TUBB | ALDH1A1 189/4885TDP1 1285/4885TSHR 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.