SCHEMBL20280574

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20012881	0.83	SLC7A5 (0.51)	ACHEBCHECHRM1CHRM2CHRM4
	SCHEMBL25812489	0.83	ALDH1A1 (0.62)	CHRM1PKMMAPK1HSD17B10SCN1A
	SCHEMBL22965811	0.83	CYP4F2 (0.49)	CHRM1PKMMAPK1HSD17B10SCN1A
	SCHEMBL10071524	0.81	PTGS2 (0.60)	CHRM1CHRM2CHRM4CHRM3PTGS1
	SCHEMBL21019793	0.80	ACHE (0.57)	ACHEBCHECHRM1MAPK1LMNA
	SCHEMBL20012830	0.80	ACHE (0.57)	ACHEBCHECHRM1CHRM2CHRM4
	Iodide SCHEMBL7261649	0.80	ACHE (0.57)	ACHEBCHECHRM1CHRM2CHRM4
	SCHEMBL3027263	0.80	ESR1 (0.64)	CHRM1CHRM2MAPK1SCN1ASCN2A
	Iodide SCHEMBL1394007	0.79	PTGS2 (0.59)	CHRM1PTGS1PTGS2LMNAESR1
	SCHEMBL5144211	0.79	ESR1 (0.66)	ACHEBCHECHRM1MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.