Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.51 |
| ▸ | EYA3 | Q99504 | 5/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | EYA2 | O00167 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20280639 | 0.84 | CYP2C19 (0.70) | CYP2C19SLC22A12EYA3TTRMEN1 | |
| SCHEMBL20280750 | 0.84 | CYP2C19 (0.70) | CYP2C19SLC22A12EYA3TTRMEN1 | |
| SCHEMBL20280676 | 0.83 | SLC22A12 (0.75) | CYP2C19SLC22A12EYA3TTRMEN1 | |
| SCHEMBL30258544 | 0.81 | CYP2C19 (0.73) | CYP2C19SLC22A12EYA3TTRMEN1 | |
| SCHEMBL30258464 | 0.81 | CYP2C19 (0.73) | CYP2C19SLC22A12EYA3TTRMEN1 | |
| SCHEMBL29104693 | 0.69 | LMNA (0.46) | MEN1KMT2ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL22072730 | 0.69 | SLC22A12 (0.88) | CYP2C19SLC22A12EYA3TTRMEN1 | |
| SCHEMBL1287381 | 0.68 | SLC22A12 (0.78) | CYP2C19SLC22A12EYA3TTRMEN1 | |
| SCHEMBL20718462 | 0.68 | EYA3 (0.54) | CYP2C19SLC22A12EYA3TTRMEN1 | |
| SCHEMBL20718463 | 0.68 | SLC22A12 (0.46) | CYP2C19SLC22A12EYA3TTRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005750-B2 | Developing potent urate transporter inhibitors: compounds designed for their uricosuric action | J-PHARMA CO., LTD. (JP) | 2018-06-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005750-B2 | Developing potent urate transporter inhibitors: compounds designed for their uricosuric action | SLCO2B1, SLCO2A1, SLC10A6 | CYP2C19 269/4885SLC22A12 19/4885EYA3 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.