Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | SLC26A4 | O43511 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825883 | 0.81 | MAPT (0.55) | LMNAHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL17912486 | 0.81 | MEN1 (0.51) | LMNAHTTGPR35SLC26A4ALDH1A1 | |
| SCHEMBL17912483 | 0.81 | EYA3 (0.48) | LMNAHTTGPR35SLC26A4ALDH1A1 | |
| SCHEMBL10938750 | 0.75 | GPR35 (0.54) | HTTGPR35ALDH1A1HPGDRAB9A | |
| SCHEMBL15020090 | 0.75 | LMNA (0.64) | LMNAHTTSLC26A4SMN1; SMN2KMT2A | |
| SCHEMBL16654658 | 0.75 | PTGS2 (0.47) | LMNAHTTGPR35SLC26A4ALDH1A1 | |
| SCHEMBL31604869 | 0.75 | SLC26A4 (0.43) | LMNAHTTSLC26A4SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11133623 | 0.74 | GPR35 (0.53) | HTTGPR35ALDH1A1HPGDRAB9A | |
| SCHEMBL24470616 | 0.73 | HTT (0.64) | LMNAHTTSLC26A4ALDH1A1HPGD | |
| SCHEMBL2083566 | 0.73 | ALDH1A1 (0.54) | LMNAHTTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |