Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489633 | 0.84 | HTT (0.44) | ALDH1A1CYP2A6MEN1KMT2AKDM4E | |
| SCHEMBL5382993 | 0.81 | SNCA (0.33) | MEN1KMT2APOLB | |
| SCHEMBL26622412 | 0.77 | HDAC8 (0.42) | HDAC8KDM4ESMN1; SMN2POLBAPOBEC3A | |
| SCHEMBL28853625 | 0.77 | HDAC8 (0.42) | ALDH1A1HDAC8MEN1KMT2AKDM4E | |
| SCHEMBL1830961 | 0.76 | NPSR1 (0.47) | HDAC8KMT2AKDM4ESMN1; SMN2BRD4 | |
| Iodide SCHEMBL26622415 | 0.75 | HDAC8 (0.41) | HDAC8KDM4ESMN1; SMN2POLBAPOBEC3A | |
| SCHEMBL29187837 | 0.73 | SMN1; SMN2 (0.42) | ALDH1A1HDAC8CYP2A6MEN1KMT2A | |
| SCHEMBL13822652 | 0.67 | — | — | |
| SCHEMBL30800829 | 0.67 | F13A1 (0.37) | ALDH1A1CYP2A6TYRKDM4ECYP2A13 | |
| SCHEMBL2026892 | 0.65 | ERAP1 (0.64) | ALDH1A1CYP2A6KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | claimed |
| US-7413579-B2 | Method for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-08-19 | — | — | US | claimed |
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | claimed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | claimed |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-04 | — | — | US | claimed |
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | claimed |
| US-20060265818-A1 | At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections | HENKEL KOMMANDITGESELLSCHAFT AUF AKLLEN (HENKEL KGAA) (DE) | 2006-11-30 | — | — | US | claimed |
| EP-1715839-A1 | AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-11-02 | — | — | EP | claimed |
| EP-1715836-A1 | METHOD FOR DYEING FIBRES CONTAINING KERATINE | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-11-02 | — | — | EP | claimed |
| EP-1433469-B1 | Composition for dyeing keratinous fibres | HENKEL KGAA (DE) | 2006-10-11 | — | — | EP | claimed |
| US-7105032-B2 | Agents used for dyeing keratinous fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-09-12 | — | — | US | claimed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | claimed |
| CN-1681470-A | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2005-10-12 | — | — | CN | claimed |
| WO-2005063178-A1 | AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-07-14 | — | — | WO | claimed |
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | HENKEL AG & CO. KGAA (DE) | 2005-07-07 | — | — | US | claimed |
| WO-2005051336-A1 | METHOD FOR DYEING FIBRES CONTAINING KERATINE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-06-09 | — | — | WO | claimed |
| EP-1433469-A1 | Composition for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| CN-115160634-B | Cationic porous material and preparation method and application thereof | 华东理工大学 | 2024-01-26 | — | — | CN | disclosed |
| EP-1430874-A2 | 4-N, N-Bis-(monohydroxyalkyl)amino-3-nitrophenol derivatives in dyeing compositions for keratinic fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | KRT18, TUBB3, DSG1 | ALDH1A1 343/4885HDAC8 415/4885CYP2A6 2072/4885 |
| US-20060265818-A1 | At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections | KRT18, CUTA, PLOD2 | ALDH1A1 159/4885HDAC8 450/4885CYP2A6 2020/4885 |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | KRT18, H1-10, COL1A1 | ALDH1A1 77/4885HDAC8 1362/4885CYP2A6 534/4885 |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | KRT18, COL1A1, CYC1 | ALDH1A1 780/4885HDAC8 289/4885CYP2A6 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.