SCHEMBL202849

SCHEMBL202849

O=C(O)c1ccc2c(c1)C1(OC2=O)c2cc(C(=O)O)c(O)c(Cl)c2Oc2c1cc(C(=O)O)c(O)c2Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 4/20 0.42
TDP1 Q9NUW8 4/20 0.42
THRB P10828 3/20 0.42
MEN1 O00255 3/20 0.42
BLM P54132 3/20 0.42
KMT2A Q03164 3/20 0.42
ACE2 Q9BYF1 2/20 0.42
PRMT1 Q99873 2/20 0.42
USP2 O75604 1/20 0.42
CDK2 P24941 1/20 0.42
CHAT P28329 1/20 0.42
BLVRB P30043 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
GNG2 P59768 1/20 0.40
GNB1 P62873 1/20 0.40
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202968 0.91 GNG2 (0.43) RECQLTDP1THRBMEN1BLM
SCHEMBL6823049 0.90 RECQL (0.43) RECQLTDP1THRBMEN1BLM
SCHEMBL3390818 0.88 TDP1 (0.41) RECQLTDP1THRBMEN1BLM
SCHEMBL29838713 0.85 MEN1 (0.39) RECQLTDP1THRBMEN1BLM
SCHEMBL16118 0.85 MEN1 (0.39) RECQLTDP1THRBMEN1BLM
SCHEMBL29353753 0.85 MEN1 (0.39) RECQLTDP1THRBMEN1BLM
SCHEMBL6415591 0.84 MEN1 (0.34) RECQLTDP1THRBMEN1BLM
SCHEMBL29401708 0.84 GNG2 (0.50) RECQLTDP1THRBMEN1BLM
SCHEMBL15019692 0.84 GNG2 (0.50) RECQLTDP1THRBMEN1BLM
SCHEMBL203192 0.81 GNG2 (0.43) RECQLTDP1THRBMEN1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2371927-B1 Fluorescent dye compounds, conjugates and uses thereof LIFE TECHNOLOGIES CORP (US) 2020-03-11 EP disclosed
US-20190168211-A1 VACUUM ASSIST FOR A MICROPLATE APPLERA CORPORATION 2019-06-06 US disclosed
EP-1802727-B1 FLUORESCENT DYE COMPOUNDS, CONJUGATES AND USES THEREOF LIFE TECHNOLOGIES CORP (US) 2018-04-04 EP disclosed
US-9745336-B2 Fluorescent dye compounds, conjugates and uses thereof APPLIED BIOSYSTEMS, LLC (US) 2017-08-29 US disclosed
US-9492820-B2 High density plate filler APPLIED BIOSYSTEMS, LLC (US) 2016-11-15 US disclosed
US-20160325284-A1 Pressure Chamber Clamp Mechanism APPLERA CORPORATION 2016-11-10 US disclosed
US-20160214102-A1 Vacuum Assist for a Microplate APPLIED BIOSYSTEMS LLC (US) 2016-07-28 US disclosed
US-9213042-B2 Vacuum assist for a microplate APPLIED BIOSYSTEMS, LLC (US) 2015-12-15 US disclosed
US-20150273469-A1 High Density Plate Filler APPLERA CORPORATION 2015-10-01 US disclosed
US-9052298-B2 High density plate filler APPLIED BIOSYSTEMS, LLC (US) 2015-06-09 US disclosed
US-20050232818-A1 Single sheet seal applicator and cartridge APPLIED BIOSYSTEMS, LLC 2005-10-20 US disclosed
US-20050231723-A1 Optical camera alignment APPLIED BIOSYSTEMS, LLC 2005-10-20 US disclosed
US-20050226771-A1 High speed microplate transfer APPLIED BIOSYSTEMS, LLC 2005-10-13 US disclosed
US-20050226780-A1 Manual seal applicator APPLIED BIOSYSTEMS, LLC 2005-10-13 US disclosed
US-20050226782-A1 High density plate filler APPLIED BIOSYSTEMS, LLC 2005-10-13 US disclosed
US-20050226779-A1 Vacuum assist for a microplate APPLIED BIOSYSTEMS, INC. 2005-10-13 US disclosed
US-20050225751-A1 Two-piece high density plate APPLIED BIOSYSTEMS, LLC 2005-10-13 US disclosed
US-20050221358-A1 Pressure chamber clamp mechanism APPLIED BIOSYSTEMS, LLC 2005-10-06 US disclosed
WO-2005028110-A2 MICROPLATES USEFUL FOR CONDUCTING THERMOCYCLED NUCLEOTIDE AMPLIFICATION APPLERA CORPORATION (US) 2005-03-31 WO disclosed
WO-2005028109-A2 MICROPLATES USEFUL FOR CONDUCTING THERMOCYCLED NUCLEOTIDE AMPLIFICATION APPLERA CORPORATION (US) 2005-03-31 WO disclosed