Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CHAT | P28329 | 1/20 | 0.41 |
| ▸ | BLVRB | P30043 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823049 | 0.89 | RECQL (0.43) | TDP1MEN1KMT2ARECQLTHRB | |
| SCHEMBL202849 | 0.88 | RECQL (0.42) | TDP1MEN1KMT2ARECQLTHRB | |
| SCHEMBL29838713 | 0.86 | MEN1 (0.39) | TDP1MEN1KMT2ARECQLTHRB | |
| SCHEMBL16118 | 0.86 | MEN1 (0.39) | TDP1MEN1KMT2ARECQLTHRB | |
| SCHEMBL29353753 | 0.86 | MEN1 (0.39) | TDP1MEN1KMT2ARECQLTHRB | |
| SCHEMBL15019692 | 0.83 | GNG2 (0.50) | TDP1MEN1KMT2ARECQLTHRB | |
| SCHEMBL29401708 | 0.83 | GNG2 (0.50) | TDP1MEN1KMT2ARECQLTHRB | |
| Succinimide SCHEMBL25268120 | 0.80 | MEN1 (0.35) | TDP1MEN1KMT2ARECQLTHRB | |
| SCHEMBL203192 | 0.80 | GNG2 (0.43) | TDP1MEN1KMT2ARECQLTHRB | |
| SCHEMBL202968 | 0.79 | GNG2 (0.43) | TDP1MEN1KMT2ARECQLTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220098289-A1 | THERAPEUTIC TARGET AND MONOCLONAL ANTIBODIES AGAINST IT FOR THE DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE | INSTITUTO DE SALUD CARLOS III (ES) | 2022-03-31 | — | — | US | disclosed |
| WO-2020165453-A1 | THERAPEUTIC TARGET AND MONOCLONAL ANTIBODIES AGAINST IT FOR THE DIAGNOSIS AND TREATMENT OF ALZHEIMER´S DISEASE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2020-08-20 | — | — | WO | disclosed |
| EP-3696192-A1 | THERAPEUTIC TARGET AND MONOCLONAL ANTIBODIES AGAINST IT FOR THE DIAGNOSIS AND TREATMENT OF ALZHEIMER´S DISEASE | Consejo Superior De Investigaciones Científicas (ES) | 2020-08-19 | — | — | EP | disclosed |
| EP-3514166-A1 | METHOD FOR THE DETECTION AND/OR QUANTIFICATION OF LUPIN BETA-CONGLUTIN ALLERGEN PROTEINS | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2019-07-24 | — | — | EP | disclosed |
| US-20140287418-A1 | COMPOSITION FOR AMPLIFYING NUCLEIC ACIDS | BIO-RAD INNOVATIONS (FR) | 2014-09-25 | — | — | US | disclosed |
| EP-1815013-B1 | COMPOSITION FOR AMPLIFYING NUCLEIC ACIDS | BIO RAD PASTEUR (FR) | 2010-12-29 | — | — | EP | disclosed |
| US-20080020396-A1 | Composition For Amplifying Nucleic Acids | BIO-RAD EUROPE GMBH (CH) | 2008-01-24 | — | — | US | disclosed |