Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 1/20 | 0.43 |
| ▸ | GNB1 | P62873 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CHAT | P28329 | 1/20 | 0.42 |
| ▸ | BLVRB | P30043 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 7/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202849 | 0.91 | RECQL (0.42) | GNG2GNB1RECQLTDP1MEN1 | |
| SCHEMBL203192 | 0.90 | GNG2 (0.43) | GNG2GNB1RECQLTDP1MEN1 | |
| SCHEMBL29831001 | 0.85 | GNG2 (0.40) | GNG2GNB1RECQLTDP1MEN1 | |
| SCHEMBL345532 | 0.85 | GNG2 (0.40) | GNG2GNB1RECQLTDP1MEN1 | |
| SCHEMBL6415591 | 0.84 | MEN1 (0.34) | GNG2GNB1RECQLTDP1MEN1 | |
| SCHEMBL6415903 | 0.81 | SMAD3 (0.35) | RECQLTDP1MEN1BLMKMT2A | |
| SCHEMBL20526266 | 0.81 | SMAD3 (0.49) | GNG2GNB1RECQLTDP1MEN1 | |
| SCHEMBL6823049 | 0.81 | RECQL (0.43) | GNG2GNB1RECQLTDP1MEN1 | |
| SCHEMBL3390818 | 0.79 | TDP1 (0.41) | GNG2GNB1RECQLTDP1MEN1 | |
| SCHEMBL3655680 | 0.78 | GNG2 (0.43) | GNG2GNB1RECQLTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371927-B1 | Fluorescent dye compounds, conjugates and uses thereof | LIFE TECHNOLOGIES CORP (US) | 2020-03-11 | — | — | EP | claimed |
| US-8729267-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2014-05-20 | — | — | US | claimed |
| US-20110250699-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | Life Technologies Corporation (US) | 2011-10-13 | — | — | US | claimed |
| EP-2371927-A1 | Fluorescent dye compounds, conjugates and uses thereof | Life Technologies Corporation (US) | 2011-10-05 | — | — | EP | claimed |
| US-7985602-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2011-07-26 | — | — | US | claimed |
| US-20090093062-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | APPLERA CORPORATION (US) | 2009-04-09 | — | — | US | claimed |
| US-20190168211-A1 | VACUUM ASSIST FOR A MICROPLATE | APPLERA CORPORATION | 2019-06-06 | — | — | US | disclosed |
| US-9745336-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2017-08-29 | — | — | US | disclosed |
| US-9492820-B2 | High density plate filler | APPLIED BIOSYSTEMS, LLC (US) | 2016-11-15 | — | — | US | disclosed |
| US-20160325284-A1 | Pressure Chamber Clamp Mechanism | APPLERA CORPORATION | 2016-11-10 | — | — | US | disclosed |
| US-20160214102-A1 | Vacuum Assist for a Microplate | APPLIED BIOSYSTEMS LLC (US) | 2016-07-28 | — | — | US | disclosed |
| US-9213042-B2 | Vacuum assist for a microplate | APPLIED BIOSYSTEMS, LLC (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150273469-A1 | High Density Plate Filler | APPLERA CORPORATION | 2015-10-01 | — | — | US | disclosed |
| US-20050226771-A1 | High speed microplate transfer | APPLIED BIOSYSTEMS, LLC | 2005-10-13 | — | — | US | disclosed |
| US-20050226780-A1 | Manual seal applicator | APPLIED BIOSYSTEMS, LLC | 2005-10-13 | — | — | US | disclosed |
| US-20050225751-A1 | Two-piece high density plate | APPLIED BIOSYSTEMS, LLC | 2005-10-13 | — | — | US | disclosed |
| US-20050226779-A1 | Vacuum assist for a microplate | APPLIED BIOSYSTEMS, INC. | 2005-10-13 | — | — | US | disclosed |
| US-20050221358-A1 | Pressure chamber clamp mechanism | APPLIED BIOSYSTEMS, LLC | 2005-10-06 | — | — | US | disclosed |
| WO-2005028110-A2 | MICROPLATES USEFUL FOR CONDUCTING THERMOCYCLED NUCLEOTIDE AMPLIFICATION | APPLERA CORPORATION (US) | 2005-03-31 | — | — | WO | disclosed |
| WO-2005028109-A2 | MICROPLATES USEFUL FOR CONDUCTING THERMOCYCLED NUCLEOTIDE AMPLIFICATION | APPLERA CORPORATION (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093062-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | GFPT1, SLC46A1, SLC7A5 | GNG2 1559/4885GNB1 1485/4885RECQL 1662/4885 |
| US-20110250699-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | GFPT1, SLC46A1, SLC7A5 | GNG2 1559/4885GNB1 1485/4885RECQL 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.