Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034196 | 0.91 | FBP1 (0.40) | ALDH1A1MEN1KMT2AFBP1MAPT | |
| SCHEMBL2034944 | 0.90 | MAPT (0.33) | TDP1ALDH1A1MEN1PSMD14PRKACA | |
| SCHEMBL2034235 | 0.86 | ABCB1 (0.39) | TDP1ALDH1A1LMNATSHR | |
| SCHEMBL2034070 | 0.86 | VCAM1 (0.37) | TDP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2029853 | 0.85 | ALDH1A1 (0.34) | TDP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2034068 | 0.85 | MEN1 (0.37) | TDP1ALDH1A1MEN1CASP6KMT2A | |
| SCHEMBL5583481 | 0.84 | TSHR (0.40) | TDP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2052797 | 0.83 | HCAR3 (0.38) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL2028578 | 0.82 | HCAR3 (0.42) | TDP1ALDH1A1MEN1KMT2AFBP1 | |
| SCHEMBL2031731 | 0.81 | POLB (0.43) | TDP1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956011-B2 | Materials and methods for the photodirected synthesis of oligonucleotide arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2011-06-07 | — | — | US | claimed |