Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | EIF4E | P06730 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028581 | 0.91 | TDP1 (0.37) | FBP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2034235 | 0.88 | ABCB1 (0.39) | ALDH1A1HPGDEIF4EHTTAKR1C3 | |
| SCHEMBL2034944 | 0.88 | MAPT (0.33) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2033475 | 0.84 | MAPT (0.47) | FBP1MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL2029622 | 0.81 | MAPT (0.43) | MAPTALDH1A1HPGDMEN1HTT | |
| SCHEMBL2034070 | 0.80 | VCAM1 (0.37) | MAPTALDH1A1HPGDMEN1HTT | |
| SCHEMBL2034068 | 0.79 | MEN1 (0.37) | MAPTALDH1A1HPGDMEN1HTT | |
| SCHEMBL2029853 | 0.79 | ALDH1A1 (0.34) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2052797 | 0.79 | HCAR3 (0.38) | MAPTALDH1A1HPGDMEN1HTT | |
| SCHEMBL5583481 | 0.79 | TSHR (0.40) | MAPTALDH1A1MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956011-B2 | Materials and methods for the photodirected synthesis of oligonucleotide arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2011-06-07 | — | — | US | claimed |