Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65534 | 0.87 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL952948 | 0.85 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL9559905 | 0.81 | ALDH1A1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL9560048 | 0.81 | ALDH1A1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL322652 | 0.81 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL63713 | 0.81 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL4336062 | 0.80 | HCAR2 (0.31) | — | |
| SCHEMBL27492219 | 0.77 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL11806871 | 0.76 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL538063 | 0.76 | TSHR (0.50) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861840-A | Novel siloxanyl acrylic monomer and gas-permeable contact lenses made therefrom | BARNES-HIND, INC. (US) | 1989-08-29 | — | — | US | claimed |
| JP-63253091-A | — | — | None | — | — | JP | disclosed |
| EP-4097155-B1 | ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | CLEARLAB SG PTE LTD (SG) | 2025-08-20 | — | — | EP | disclosed |
| US-12037463-B2 | Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof | Clearlab Sg Pte Ltd. (SG) | 2024-07-16 | — | — | US | disclosed |
| US-12024597-B2 | Wound dressings comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof | Clearlab Sg Pte Ltd. (SG) | 2024-07-02 | — | — | US | disclosed |
| US-20230227613-A1 | ANTIMICROBIAL OPHTHALMIC DEVICES COMPRISING POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | CLEARLAB SG PTE LTD (SG) | 2023-07-20 | — | — | US | disclosed |
| US-20230212357-A1 | WOUND DRESSINGS COMPRISING POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | CLEARLAB SG PTE LTD (SG) | 2023-07-06 | — | — | US | disclosed |
| US-11649325-B2 | Actinically-crosslinkable polysiloxane-polyglycerol block copolymers and methods of making and use thereof | Clearlab Sg Pte Ltd. (SG) | 2023-05-16 | — | — | US | disclosed |
| EP-4097155-A1 | ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | Clearlab SG Pte Ltd (SG) | 2022-12-07 | — | — | EP | disclosed |
| US-20210246270-A1 | ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | Clearlab Sg Pte Ltd. (SG) | 2021-08-12 | — | — | US | disclosed |
| US-10329486-B2 | Cyanostilbenes | ROLIC AG (CH) | 2019-06-25 | — | — | US | disclosed |
| EP-3004050-A1 | CYANOSTILBENES | Rolic AG (CH) | 2016-04-13 | — | — | EP | disclosed |
| US-20160083655-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2016-03-24 | — | — | US | disclosed |
| WO-2014191292-A1 | CYANOSTILBENES | ROLIC AG (CH) | 2014-12-04 | — | — | WO | disclosed |
| US-7959990-B2 | Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light | ROLIC AG (CH) | 2011-06-14 | — | — | US | disclosed |
| US-20080274304-A1 | Functionalized Photoreactive Compounds | ROLIC AG (CH) | 2008-11-06 | — | — | US | disclosed |
| EP-1764405-A1 | Functionalized photoreactive compounds | Rolic AG (CH) | 2007-03-21 | — | — | EP | disclosed |
| US-4948855-A | COPOLYMER OF UNSATURATED SILOXANYLALKOXYESTER AND VINYL SILFONE | PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) | 1990-08-14 | — | — | US | disclosed |
| US-4861840-A | Novel siloxanyl acrylic monomer and gas-permeable contact lenses made therefrom | BARNES-HIND, INC. (US) | 1989-08-29 | — | — | US | disclosed |
| JP-S63253091-A | ((METH)ACRYLOXYALKOXY)SILANE HAVING TRIMETHYLSILOXY GROUP | TOSHIBA SILICONE CO LTD | 1988-10-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274304-A1 | Functionalized Photoreactive Compounds | PCNA, PIN1, MAP1LC3C | TSHR 4847/4885ALDH1A1 147/4885 |
| US-20160083655-A1 | CYANOSTILBENES | LATS1, LATS2, CRY1 | TSHR 4718/4885ALDH1A1 2838/4885 |
| US-10329486-B2 | Cyanostilbenes | LATS1, LATS2, CRY1 | TSHR 4718/4885ALDH1A1 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.