Sugi Predict

Sugi Predict / Compounds / SCHEMBL202890

SCHEMBL202890

SCHEMBL202890

COC(C)=C(C(=O)O)c1ccccc1Oc1cc(Oc2ccccc2)ccn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK8 P45983 1/20 0.45
▸ MAPK10 P53779 1/20 0.45
▸ GCK P35557 2/20 0.44
▸ TDP1 Q9NUW8 1/20 0.41
▸ PYGL P06737 1/20 0.39
▸ PYGM P11217 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ MEN1 O00255 4/20 0.39
▸ KMT2A Q03164 4/20 0.39
▸ CASP3 P42574 1/20 0.39
▸ SENP8 Q96LD8 1/20 0.39
▸ SENP7 Q9BQF6 1/20 0.39
▸ SENP6 Q9GZR1 1/20 0.39
▸ SRC P12931 1/20 0.39
▸ TGFBR1 P36897 1/20 0.39
▸ GAA P10253 2/20 0.38
▸ TSHR P16473 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ MAPT P10636 1/20 0.38
▸ CTNNB1 P35222 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202889 0.90 MAPK8 (0.45) MAPK8MAPK10GCKTDP1RAB9A
SCHEMBL7691501 0.87 PIN1 (0.43) MAPK8MAPK10GCKPYGLPYGM
SCHEMBL8584984 0.85 GCK (0.45) MAPK8MAPK10GCKTDP1PYGL
SCHEMBL203541 0.83 SRC (0.38) MAPK8MAPK10MEN1KMT2ASRC
SCHEMBL203718 0.83 CTNNB1 (0.54) MAPK8TDP1RAB9AMEN1KMT2A
SCHEMBL8844349 0.82 KDM4E (0.37) MAPK8MAPK10TDP1RAB9AMEN1
SCHEMBL205379 0.81 MEN1 (0.49) TDP1PYGLPYGMRAB9AMEN1
SCHEMBL2847819 0.80 MAPK8 (0.45) MAPK8MAPK10GCKTDP1RAB9A
SCHEMBL709626 0.80 ALDH1A1 (0.44) RAB9AMEN1KMT2ASRCTGFBR1
SCHEMBL27075764 0.80 ALDH1A1 (0.44) RAB9AMEN1KMT2ASRCTGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 — — US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 — — US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 — — US disclosed
US-9314030-B2 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS INC. (US) 2016-04-19 — — US disclosed
EP-2670239-B1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS SANITIZED AG (CH) 2015-08-12 — — EP disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 — — US disclosed
US-20150056258-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2015-02-26 — — US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 — — US disclosed
WO-2014102228-A1 FORMULATION FOR THE ANTIMICROBIAL TREATMENT OF POLYMER COMPOSITIONS SANITIZED AG (CH) 2014-07-03 — — WO disclosed
EP-2749167-A1 Formulation for the antimicrobial treatment of polyvinyl chloride compositions Sanitized AG (CH) 2014-07-02 — — EP disclosed
WO-1997008140-A1 N-SULFONYLIMINODITHIO COMPOUNDS USEFUL FOR PLANT AND MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 — — WO disclosed
WO-1996032235-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1996-10-17 — — WO disclosed
WO-1996029314-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1996-09-26 — — WO disclosed
EP-0730517-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1996-09-11 — — EP disclosed
WO-1996025044-A1 S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1996-08-22 — — WO disclosed
WO-1996010915-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-04-18 — — WO disclosed
EP-0690894-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AG (DE) 1996-01-10 — — EP disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 — — WO disclosed
WO-1995011786-A1 TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-05-04 — — WO disclosed
WO-1994021734-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1994-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 MAPK8 4031/4885MAPK10 4047/4885GCK 1212/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 MAPK8 4077/4885MAPK10 3710/4885GCK 1637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.