SCHEMBL202889

SCHEMBL202889

CC(C)=C(C(=O)O)c1ccccc1Oc1cc(Oc2ccccc2)ccn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.45
MAPK10 P53779 1/20 0.45
GCK P35557 2/20 0.43
CTNNB1 P35222 1/20 0.40
GAA P10253 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
LOXL2 Q9Y4K0 3/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
LOX P28300 1/20 0.36
RAB9A P51151 1/20 0.36
ACACB O00763 1/20 0.36
GRM2 Q14416 1/20 0.36
CYSLTR1 Q9Y271 1/20 0.36
FFAR1 O14842 1/20 0.36
MEN1 O00255 1/20 0.36
CASP3 P42574 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202890 0.90 MAPK8 (0.45) MAPK8MAPK10GCKCTNNB1GAA
SCHEMBL7691499 0.86 POLB (0.39) GCKGAARAB9A
SCHEMBL8584982 0.84 GCK (0.45) MAPK8MAPK10GCKGAATSHR
SCHEMBL2847819 0.83 MAPK8 (0.45) MAPK8MAPK10GCKCTNNB1GAA
SCHEMBL203540 0.82 PKM (0.36) MAPK8MAPK10GAATSHRTDP1
SCHEMBL203717 0.81 CTNNB1 (0.59) CTNNB1GAATSHRALDH1A1HSD17B10
SCHEMBL2847823 0.80 MAPK8 (0.42) MAPK8MAPK10GCKCTNNB1GAA
SCHEMBL2847813 0.80 MAPK8 (0.42) MAPK8MAPK10GCKCTNNB1GAA
SCHEMBL205378 0.79 MEN1 (0.52) CTNNB1GAATSHRTDP1ALDH1A1
SCHEMBL7062543 0.78 MAPK8 (0.45) MAPK8MAPK10GCKCTNNB1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
US-9314030-B2 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS INC. (US) 2016-04-19 US disclosed
EP-2670239-B1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS SANITIZED AG (CH) 2015-08-12 EP disclosed
US-20150056258-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2015-02-26 US disclosed
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8445519-B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof AVENTIS AGRICULTURE (FR) 2013-05-21 US disclosed
WO-1997008140-A1 N-SULFONYLIMINODITHIO COMPOUNDS USEFUL FOR PLANT AND MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed
WO-1996032235-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1996-10-17 WO disclosed
WO-1996029314-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1996-09-26 WO disclosed
EP-0730517-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1996-09-11 EP disclosed
WO-1996025044-A1 S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1996-08-22 WO disclosed
WO-1996010915-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-04-18 WO disclosed
EP-0690894-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AG (DE) 1996-01-10 EP disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO disclosed
WO-1995011786-A1 TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-05-04 WO disclosed
WO-1994021734-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 MAPK8 4031/4885MAPK10 4047/4885GCK 1212/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 MAPK8 4077/4885MAPK10 3710/4885GCK 1637/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 MAPK8 675/4885MAPK10 831/4885GCK 3827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.