Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573426 | 0.92 | TP53 (0.46) | PTGS1PTGS2NFE2L2ALOX5TUBB4A | |
| SCHEMBL6573201 | 0.92 | TP53 (0.46) | PTGS1PTGS2NFE2L2ALOX5TUBB4A | |
| SCHEMBL6573320 | 0.92 | TP53 (0.46) | PTGS1PTGS2NFE2L2ALOX5TUBB4A | |
| SCHEMBL25911510 | 0.83 | TSHR (0.71) | PTGS1PTGS2NFE2L2ALOX5TSHR | |
| SCHEMBL2033159 | 0.82 | ALDH1A1 (0.42) | PTGS1PTGS2NFE2L2ALOX5TSHR | |
| SCHEMBL14363044 | 0.80 | NFE2L2 (0.71) | PTGS1PTGS2NFE2L2ALOX5TUBB4A | |
| SCHEMBL6876801 | 0.80 | ALDH1A1 (0.44) | PTGS1PTGS2NFE2L2ALOX5TSHR | |
| SCHEMBL7759021 | 0.80 | ALDH1A1 (0.44) | PTGS1PTGS2NFE2L2ALOX5TSHR | |
| SCHEMBL13913121 | 0.79 | TUBB1 (0.61) | PTGS1PTGS2NFE2L2ALOX5TSHR | |
| SCHEMBL8099032 | 0.79 | TTR (0.48) | PTGS1PTGS2NFE2L2ALOX5TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960557-B2 | Asymmetric dendrimers | ISIS INNOVATION LIMITED (GB) | 2011-06-14 | — | — | US | disclosed |
| US-20090326238-A1 | ASYMMETRIC DENDRIMERS | ISIS INNOVATION LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| US-7537842-B2 | Asymmetric dendrimers | ISIS INNOVATION LIMITED (GB) | 2009-05-26 | — | — | US | disclosed |
| EP-1373431-B1 | ASYMMETRIC DENDRIMERS | ISIS INNOVATION (GB) | 2006-10-18 | — | — | EP | disclosed |
| US-20040110029-A1 | Asymmetric dendrimers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2004-06-10 | — | — | US | disclosed |
| EP-1373431-A1 | ASYMMETRIC DENDRIMERS | ISIS INNOVATION LIMITED (GB) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002066575-A1 | ASYMMETRIC DENDRIMERS | ISIS INNOVATION LIMITED (GB) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326238-A1 | ASYMMETRIC DENDRIMERS | DNM2, DYNLL2, DNM1 | PTGS1 3556/4885PTGS2 2471/4885NFE2L2 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.