SCHEMBL20299840

SCHEMBL20299840

CC1(C(N)C(=O)O)OCCO1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
GRM1 Q13255 3/20 0.39
GRM5 P41594 1/20 0.33
GRM2 Q14416 1/20 0.33
GRM4 Q14833 1/20 0.33
SLC7A5 Q01650 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20299839 1.00 SLC1A2 (0.41) SLC1A2SLC1A1GRM1GRM5GRM2
SCHEMBL3384819 0.74 TP53 (0.33)
SCHEMBL31374928 0.74 SLC1A2 (0.43) SLC1A2SLC1A1GRM1GRM5GRM2
SCHEMBL10211889 0.74 SLC1A2 (0.43) SLC1A2SLC1A1GRM1GRM5GRM2
Acetic Acid SCHEMBL23462294 0.70 SLC1A2 (0.47) SLC1A2SLC1A1GRM1GRM5GRM2
Acetic Acid SCHEMBL23462296 0.70 SLC1A2 (0.47) SLC1A2SLC1A1GRM1GRM5GRM2
SCHEMBL2160390 0.70 ALDH1A1 (0.33)
SCHEMBL17867349 0.69
SCHEMBL12634606 0.69
SCHEMBL12333137 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4570317-A2 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE Intervet International B.V. (NL) 2025-06-18 EP disclosed
US-12077488-B2 Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection INTERVET INC. (US) 2024-09-03 US disclosed
CN-110072844-B Compounds for the treatment of infection by Mannheimia haemolytica or histophilus somni 英特维特国际股份有限公司 2023-06-02 CN disclosed
US-20230000813-A1 COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INC. (US) 2023-01-05 US disclosed
CN-110300578-B Compounds for the treatment of respiratory diseases in cattle or pigs 英特维特国际股份有限公司 2022-12-13 CN disclosed
US-11406617-B2 Compounds for the treatment of bovine or swine respiratory disease INTERVET INC. (US) 2022-08-09 US disclosed
US-20220041547-A1 Compounds Useful for Treating a Mannheimia Haemolytica or Histophilus Somni Infection INTERVET INC. (US) 2022-02-10 US disclosed
US-11034650-B2 Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection INTERVET INC. (US) 2021-06-15 US disclosed
US-20200085779-A1 Compounds for the Treatment of Bovine or Swine Respiratory Disease INTERVET INC. (US) 2020-03-19 US disclosed
US-20190352256-A1 Compounds Useful for Treating a Mannheimia Haemolytica or Histophilus Somni Infection INTERVET INC. (US) 2019-11-21 US disclosed
EP-3558284-A2 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE Intervet International B.V. (NL) 2019-10-30 EP disclosed
EP-3558939-A1 COMPOUNDS USEFUL FOR TREATING A MANNHEIMIA HAEMOLYTICA OR HISTOPHILUS SOMNI INFECTION Intervet International B.V. (NL) 2019-10-30 EP disclosed
WO-2018115432-A2 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INTERNATIONAL B.V. (NL) 2018-06-28 WO disclosed
WO-2018115421-A1 COMPOUNDS USEFUL FOR TREATING A MANNHEIMIA HAEMOLYTICA OR HISTOPHILUS SOMNI INFECTION INTERVET INTERNATIONAL B.V. (NL) 2018-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12077488-B2 Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection SORD, HEXD, SNRPD1 SLC1A2 4453/4885SLC1A1 4471/4885GRM1 2622/4885
US-20220041547-A1 Compounds Useful for Treating a Mannheimia Haemolytica or Histophilus Somni Infection SORD, HEXD, SNRPD1 SLC1A2 4453/4885SLC1A1 4471/4885GRM1 2622/4885
US-11034650-B2 Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection HEXD, SORD, SDHA SLC1A2 4204/4885SLC1A1 4366/4885GRM1 2650/4885
US-11406617-B2 Compounds for the treatment of bovine or swine respiratory disease PIGS, BTD, PPARD SLC1A2 4039/4885SLC1A1 3083/4885GRM1 2585/4885
US-20190352256-A1 Compounds Useful for Treating a Mannheimia Haemolytica or Histophilus Somni Infection HEXD, SORD, SDHA SLC1A2 4204/4885SLC1A1 4366/4885GRM1 2650/4885
US-20230000813-A1 COMPOUND FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE PIGS, BTD, BRD1 SLC1A2 4174/4885SLC1A1 3475/4885GRM1 2365/4885
US-20200085779-A1 Compounds for the Treatment of Bovine or Swine Respiratory Disease PIGS, BTD, PPARD SLC1A2 4039/4885SLC1A1 3083/4885GRM1 2585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.