Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154804 | 0.94 | RIPK2 (0.33) | ADORA2AADORA3ADORA1ADORA2B | |
| Hydrochloric Acid SCHEMBL4898580 | 0.92 | RIPK2 (0.32) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7154076 | 0.67 | MAPK9 (0.44) | — | |
| SCHEMBL2953126 | 0.66 | ADORA2A (0.47) | ADORA2AADORA3ADORA1ADORA2BRPS6KB1 | |
| SCHEMBL2945103 | 0.64 | RET (0.36) | ADORA2AADORA3ADORA1ADORA2BRPS6KB1 | |
| SCHEMBL3084463 | 0.62 | — | — | |
| SCHEMBL4263641 | 0.61 | HCAR1 (0.42) | ADORA1HCAR1CSNK1A1CLK2LIMK1 | |
| SCHEMBL1551877 | 0.60 | ADORA2A (0.42) | ADORA2AADORA3ADORA1ADORA2BROCK1 | |
| SCHEMBL15545185 | 0.60 | ADORA2A (0.42) | ADORA2AADORA3ADORA1ADORA2BROCK1 | |
| SCHEMBL4263642 | 0.59 | PI4KA (0.43) | ADORA2AADORA3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025160-A1 | OXEPANE NUCLEOSIDES AND OLIGONUCLEOTIDES, USES THEREOF AND METHODS OF MAKING THE SAME | MCGILL UNIVERSITY (CA) | 2008-03-06 | — | — | WO | claimed |
| US-9572898-B2 | Functionalized fluorine containing phthalocyanine molecules | SETON HALL UNIVERSITY (US) | 2017-02-21 | — | — | US | disclosed |
| US-20150071862-A1 | FUNCTIONALIZED FLUORINE CONTAINING PHTHALOCYANINE MOLECULES | SETON HALL UNIVERSITY | 2015-03-12 | — | — | US | disclosed |
| US-20140163085-A1 | Oligonucleotide Inhibitors with Chimeric Backbone and 2-Amino-2'-Deoxyadenosine | PHARMAXIS LTD (AU) | 2014-06-12 | — | — | US | disclosed |
| CN-102099474-B | Oligonucleotides for treating inflammation and neoplastic cell proliferation | TOPIGEN PHARMACEUTICALS INC | 2014-05-28 | — | — | CN | disclosed |
| US-20140018408-A1 | OLIGONUCLEOTIDES FOR TREATING INFLAMMATION AND NEOPLASTIC CELL PROLIFERATION | PAQUET LUC (CA) | 2014-01-16 | — | — | US | disclosed |
| EP-2678431-A1 | OLIGONUCLEOTIDE INHIBITORS WITH CHIMERIC BACKBONE AND 2-AMINO-2'-DEOXYADENOSINE | PharmAxis Ltd (AU) | 2014-01-01 | — | — | EP | disclosed |
| US-8470999-B2 | Oligonucleotides for treating inflammation and neoplastic cell proliferation | PAQUET LUC (CA) | 2013-06-25 | — | — | US | disclosed |
| WO-2012113067-A1 | OLIGONUCLEOTIDE INHIBITORS WITH CHIMERIC BACKBONE AND 2-AMINO-2'-DEOXYADENOSINE | PHARMAXIS LTD (AU) | 2012-08-30 | — | — | WO | disclosed |
| US-20110144183-A1 | OLIGONUCLEOTIDES FOR TREATING INFLAMMATION AND NEOPLASTIC CELL PROLIFERATION | PAQUET LUC | 2011-06-16 | — | — | US | disclosed |
| CN-102099474-A | Oligonucleotides for treating inflammation and neoplastic cell proliferation | TOPIGEN PHARMACEUTICALS INC | 2011-06-15 | — | — | CN | disclosed |
| WO-2008025160-A1 | OXEPANE NUCLEOSIDES AND OLIGONUCLEOTIDES, USES THEREOF AND METHODS OF MAKING THE SAME | MCGILL UNIVERSITY (CA) | 2008-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150071862-A1 | FUNCTIONALIZED FLUORINE CONTAINING PHTHALOCYANINE MOLECULES | ROS1, CD47, TP53 | ADORA2A 4066/4885ADORA3 4196/4885ADORA1 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.