Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23942265 | 0.77 | GPR3 (0.48) | KDM4EALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL17151156 | 0.76 | APP (0.54) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL14289088 | 0.73 | GPR3 (0.43) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL1640925 | 0.73 | POLB (0.52) | KDM4EALDH1A1CASP1MAPTKMT2A | |
| SCHEMBL3485822 | 0.73 | GPR3 (0.59) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL14059374 | 0.72 | LRRK2 (0.56) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL24392242 | 0.72 | ACHE (0.45) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL11732580 | 0.69 | GPR3 (0.54) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL27698896 | 0.69 | DCPS (0.57) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| Benzonaphthyridine SCHEMBL30897319 | 0.68 | GPR3 (1.00) | KDM4EALDH1A1HSD17B10HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018116072-A1 | HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2018-06-28 | — | — | WO | disclosed |