SCHEMBL2030267

SCHEMBL2030267

C=C(C)C(=O)OCCN=C=O.CCCCNC(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.47
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2036704 0.95 TSHR (0.49) ACHETSHR
SCHEMBL9472629 0.81 ACHE (0.43) ACHETSHRTHRB
SCHEMBL9472441 0.80 ACHE (0.43) ACHETSHR
SCHEMBL8928140 0.80 TSHR (0.54) ACHETSHRTHRB
SCHEMBL4190885 0.80 ACHE (0.73) ACHETSHRTHRB
SCHEMBL4087391 0.80 THRB (0.55) ACHETSHRTHRB
SCHEMBL15941866 0.80 THRB (0.48) TSHRTHRB
SCHEMBL15715 0.80 THRB (0.48) TSHRTHRB
SCHEMBL17225745 0.79 TSHR (0.57) ACHETSHRTHRB
SCHEMBL15834868 0.79 ACHE (0.72) ACHETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3004050-B1 CYANOSTILBENES ROLIC TECH AG (CH) 2020-09-02 EP disclosed
US-10329486-B2 Cyanostilbenes ROLIC AG (CH) 2019-06-25 US disclosed
CN-105567260-B Functionalized photoreactive compounds 罗利克有限公司 2018-09-11 CN disclosed
EP-3004050-A1 CYANOSTILBENES Rolic AG (CH) 2016-04-13 EP disclosed
US-20160083655-A1 CYANOSTILBENES ROLIC AG (CH) 2016-03-24 US disclosed
WO-2014191292-A1 CYANOSTILBENES ROLIC AG (CH) 2014-12-04 WO disclosed
US-7959990-B2 Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light ROLIC AG (CH) 2011-06-14 US disclosed
EP-1928979-B1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2009-03-04 EP disclosed
US-20080274304-A1 Functionalized Photoreactive Compounds ROLIC AG (CH) 2008-11-06 US disclosed
EP-1764405-A1 Functionalized photoreactive compounds Rolic AG (CH) 2007-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274304-A1 Functionalized Photoreactive Compounds PCNA, PIN1, MAP1LC3C ACHE 4372/4885TSHR 4847/4885THRB 4831/4885
US-20160083655-A1 CYANOSTILBENES LATS1, LATS2, CRY1 ACHE 2348/4885TSHR 4718/4885THRB 4281/4885
US-10329486-B2 Cyanostilbenes LATS1, LATS2, CRY1 ACHE 2348/4885TSHR 4718/4885THRB 4281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.