Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510468 | 0.85 | ABL1 (0.53) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL1266209 | 0.83 | KDM4E (0.54) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL22288456 | 0.83 | GAA (0.51) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL29942878 | 0.83 | KDM4E (0.54) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL4770167 | 0.83 | GABRP (0.65) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL14956928 | 0.83 | ALDH1A1 (0.47) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL23797063 | 0.81 | NNMT (0.53) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL2032206 | 0.81 | ABL1 (0.53) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL15057962 | 0.81 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL18555299 | 0.81 | KDM4E (0.46) | ALDH1A1GAAKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005741-B2 | Therapeutic compounds | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-06-26 | — | — | US | disclosed |
| CN-101701031-A | Polypeptide condensing agent and synthesis method thereof | CHANGZHOU NANJING UNIVERSITY H | 2010-05-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005741-B2 | Therapeutic compounds | IAPP, PARK7, NLN | ALDH1A1 854/4885GAA 50/4885KDM4E 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.