Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212233 | 0.81 | CXCR3 (0.41) | KDM4EALDH1A1POLBTAAR1HTR2A | |
| SCHEMBL302475 | 0.78 | SMN1; SMN2 (0.51) | KDM4ECYP11B1CYP11B2SMN1; SMN2TAAR1 | |
| SCHEMBL1244075 | 0.67 | ALDH1A1 (0.73) | KDM4EALDH1A1POLBLMNAHTT | |
| SCHEMBL5257237 | 0.64 | ALDH1A1 (0.69) | KDM4EALDH1A1POLBLMNARAB9A | |
| SCHEMBL578497 | 0.64 | LMNA (0.67) | KDM4EALDH1A1POLBLMNARAB9A | |
| SCHEMBL1241262 | 0.64 | ALDH1A1 (0.57) | KDM4EALDH1A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL1239274 | 0.64 | HRH3 (0.74) | KDM4EALDH1A1POLBSMN1; SMN2TNIK | |
| SCHEMBL12220123 | 0.64 | KDM4E (0.47) | KDM4EALDH1A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL1241202 | 0.64 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2TNIKMEN1 | |
| Bromide SCHEMBL2530199 | 0.63 | KDM4E (0.46) | KDM4EALDH1A1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179233-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179233-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | KDM4E 3160/4885ALDH1A1 3159/4885GALR3 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.