Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207442 | 0.91 | TSHR (0.38) | CYP3A4TDP1DRD1GAA | |
| SCHEMBL101880 | 0.83 | CYP3A4 (0.50) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL28765143 | 0.83 | CYP3A4 (0.55) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL29375055 | 0.81 | CYP3A4 (0.48) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL31153795 | 0.81 | CYP3A4 (0.48) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL31059892 | 0.81 | CYP3A4 (0.48) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL17674561 | 0.81 | CYP3A4 (0.48) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL2142709 | 0.81 | CYP3A4 (0.48) | CYP3A4TDP1DRD1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL2126739 | 0.79 | CYP3A4 (0.46) | CYP3A4TDP1DRD1ESR1ESR2 | |
| Bromide SCHEMBL4290668 | 0.79 | CYP3A4 (0.46) | CYP3A4TDP1DRD1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299383-B | Method for synthesizing dibenzothiophene compound by palladium-catalyzed one-pot method | 南京邮电大学 | 2023-02-14 | — | — | CN | claimed |
| CN-112225697-B | Preparation method of enantiomer pure chloroquine and chloroquine phosphate | 宁波大学 | 2023-01-03 | — | — | CN | claimed |
| CN-115490613-A | Preparation method of aromatic nitrile compound | 浙江工业大学 | 2022-12-20 | — | — | CN | claimed |
| CN-110156710-B | Preparation method of polysubstituted oxazole compound | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2022-10-28 | — | — | CN | claimed |
| CN-111574567-A | Rigid heterocyclic compound, preparation method and application thereof, phosphine-containing sulfonamide compound and preparation method thereof | 中山大学 | 2020-08-25 | — | — | CN | claimed |
| CN-112480048-B | Compound, liquid crystal medium, liquid crystal display element and liquid crystal display | 石家庄诚志永华显示材料有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-115558093-B | Catalyst and method for synthesizing biodegradable polyester by air oxidation of 1, 4-butanediol | 化学与精细化工广东省实验室 | 2023-08-22 | — | — | CN | disclosed |
| CN-111825722-B | Saturated red-light-emitting fluorenyl benzoquinoline iridium complex | 北京印刷学院 | 2023-06-09 | — | — | CN | disclosed |
| CN-110117264-B | Phenyl sulfone derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-108299383-B | Method for synthesizing dibenzothiophene compound by palladium-catalyzed one-pot method | 南京邮电大学 | 2023-02-14 | — | — | CN | disclosed |
| CN-112225697-B | Preparation method of enantiomer pure chloroquine and chloroquine phosphate | 宁波大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-115558093-A | Catalyst and method for synthesizing biodegradable polyester by air oxidation of 1, 4-butanediol | 化学与精细化工广东省实验室 | 2023-01-03 | — | — | CN | disclosed |
| US-20090227634-A1 | Pyrazole Derivatives as 5-LO-Inhibitors | PFIZER INC. | 2009-09-10 | — | — | US | disclosed |
| EP-2097407-A1 | PYRAZOLE ANALOGS | Pfizer Products Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2009069044-A1 | PYRAZOLE DERIVATIVES AS 5-LO INHIBITORS | PFIZER INC. (US) | 2009-06-04 | — | — | WO | disclosed |
| EP-2029573-A1 | DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS | BASF SE (DE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2008065493-A1 | PYRAZOLE ANALOGS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080125474-A1 | Pyrazole Analogs | PFIZER INC. | 2008-05-29 | — | — | US | disclosed |
| WO-2007138051-A1 | DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS | BASF SE (DE) | 2007-12-06 | — | — | WO | disclosed |
| US-6235937-B1 | Process for the preparation of nitrodiphenylamines | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227634-A1 | Pyrazole Derivatives as 5-LO-Inhibitors | ALOX5, ALOX15, CYP3A5 | CYP3A4 25/4885TDP1 2233/4885DRD1 3559/4885 |
| US-20080125474-A1 | Pyrazole Analogs | IL33, CFTR, HRH1 | CYP3A4 28/4885TDP1 2884/4885DRD1 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.