SCHEMBL4207442

SCHEMBL4207442

c1ccc(Oc2cccc(P(c3ccccc3)c3ccccc3)c2P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
LTA4H P09960 1/20 0.38
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM1A O60341 2/20 0.38
DPP4 P27487 1/20 0.38
HRH1 P35367 1/20 0.36
CTNNB1 P35222 1/20 0.36
DRD1 P21728 2/20 0.36
TSPO P30536 1/20 0.36
ALDH1A1 P00352 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
RIPK1 Q13546 1/20 0.35
HPGD P15428 1/20 0.35
TLR4 O00206 1/20 0.35
TLR2 O60603 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203164 0.91 CYP3A4 (0.42) CYP3A4TDP1GAADRD1
SCHEMBL10976813 0.85 TSHR (0.44) TSHRLTA4HCYP3A4TDP1LMNA
SCHEMBL1838565 0.81 TSHR (0.44) TSHRLTA4HCYP3A4TDP1LMNA
SCHEMBL6288573 0.78 LTA4H (0.50) TSHRLTA4HLMNAGAAKMT2A
SCHEMBL28765143 0.78 CYP3A4 (0.55) CYP3A4TDP1GAADRD1
SCHEMBL16449662 0.77 CYP3A4 (0.41) TSHRLTA4HCYP3A4TDP1LMNA
SCHEMBL101880 0.74 CYP3A4 (0.50) TSHRLTA4HCYP3A4TDP1GAA
SCHEMBL1840257 0.74 LTA4H (0.50) TSHRLTA4HLMNAGAAKMT2A
SCHEMBL17674561 0.72 CYP3A4 (0.48) TSHRLTA4HCYP3A4TDP1GAA
SCHEMBL31059892 0.72 CYP3A4 (0.48) TSHRLTA4HCYP3A4TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4303243-A1 CURABLE RESIN COMPOSITION, ACTIVE ENERGY RAY CURABLE RESIN COMPOSITION, CURED PRODUCT, AND ARTICLE DIC CORPORATION (JP) 2024-01-10 EP disclosed
US-10081650-B2 Metal oxide-organic hybrid materials for heterogeneous catalysis and methods of making and using thereof YALE UNIVERSITY (US) 2018-09-25 US disclosed
CN-103797017-B Copper(I) complexes for optoelectronic devices 辛诺拉有限公司 2017-02-15 CN disclosed
US-9266906-B2 Copper(I) complexes for optoelectronic devices CYNORA GMBH (DE) 2016-02-23 US disclosed
EP-2729477-B1 COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2016-01-20 EP disclosed
US-20150065339-A1 METAL OXIDE-ORGANIC HYBRID MATERIALS FOR HETEROGENEOUS CATALYSIS AND METHODS OF MAKING AND USING THEREOF NATIONAL SCIENCE FOUNDATION 2015-03-05 US disclosed
US-20140235006-A1 COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-21 US disclosed
EP-2729477-A1 COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES cynora GmbH (DE) 2014-05-14 EP disclosed
WO-2013007707-A1 COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2013-01-17 WO disclosed
US-20090030038-A1 Novel 8-Sulfonylamino-3 Aminosubstituted Chroman or Tetrahydronaphtalene Derivatives Modulating the 5Ht6 Receptor ASTRAZENECA AB (SE) 2009-01-29 US disclosed
EP-1888517-A1 NOVEL 8-SULFONYLAMINO-3 AMINOSUBSTITUTED CHROMAN OR TETRAHYDRONAPHTALENE DERIVATIVES MODULATING THE 5HT6 RECEPTOR AstraZeneca AB (SE) 2008-02-20 EP disclosed
WO-2006126939-A1 NOVEL 8-SULFONYLAMINO-3 AMINOSUBSTITUTED CHROMAN OR TETRAHYDRONAPHTALENE DERIVATIVES MODULATING THE 5HT6 RECEPTOR ASTRAZENECA AB (SE) 2006-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030038-A1 Novel 8-Sulfonylamino-3 Aminosubstituted Chroman or Tetrahydronaphtalene Derivatives Modulating the 5Ht6 Receptor HTR6, HTR1A, HTR1D TSHR 173/4885LTA4H 1277/4885CYP3A4 657/4885
US-10081650-B2 Metal oxide-organic hybrid materials for heterogeneous catalysis and methods of making and using thereof SOD1, SOD3, AS3MT TSHR 2923/4885LTA4H 4430/4885CYP3A4 2689/4885
US-20150065339-A1 METAL OXIDE-ORGANIC HYBRID MATERIALS FOR HETEROGENEOUS CATALYSIS AND METHODS OF MAKING AND USING THEREOF SOD1, SOD3, AS3MT TSHR 2923/4885LTA4H 4430/4885CYP3A4 2689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.