Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 6/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.47 |
| ▸ | DTYMK | P23919 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20325237 | 0.87 | RNASEL (0.48) | RNASEL | |
| SCHEMBL20327591 | 0.86 | FUT5 (0.47) | RNASELSTING1 | |
| SCHEMBL21539917 | 0.85 | ALDH1A1 (0.51) | RNASELSTING1DTYMK | |
| SCHEMBL21540016 | 0.85 | ALDH1A1 (0.51) | RNASELSTING1DTYMK | |
| SCHEMBL20782764 | 0.85 | TERT (0.53) | RNASEL | |
| SCHEMBL21540009 | 0.85 | TERT (0.53) | RNASEL | |
| SCHEMBL20324868 | 0.85 | TERT (0.53) | RNASEL | |
| SCHEMBL20325223 | 0.85 | TERT (0.53) | RNASEL | |
| SCHEMBL20325230 | 0.84 | STING1 (0.46) | RNASELSTING1DTYMK | |
| SCHEMBL20325238 | 0.84 | RNASEL (0.47) | RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118664-A1 | COMBINATIONS OF PD-1 ANTAGONISTS AND CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |