Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18541156 | 0.85 | TRPV1 (0.65) | TRPV1TRPM8CYP19A1 | |
| SCHEMBL3033238 | 0.80 | TRPM8 (0.51) | TRPV1TRPM8KCNA5ALDH1A1HPGD | |
| SCHEMBL24540260 | 0.78 | TRPM8 (0.53) | TRPV1TRPM8P2RX4 | |
| SCHEMBL17363765 | 0.78 | KCNA5 (0.46) | TRPV1TRPM8KCNA5ALDH1A1HPGD | |
| Menthol SCHEMBL8187948 | 0.77 | TRPM8 (0.47) | TRPV1TRPM8KCNA5ALDH1A1HPGD | |
| SCHEMBL19020350 | 0.77 | CYP19A1 (0.53) | TRPM8KCNA5ALDH1A1HPGDLMNA | |
| SCHEMBL4885292 | 0.76 | EPHX1 (0.46) | TRPV1TRPM8ALDH1A1HPGDLMNA | |
| SCHEMBL23718853 | 0.76 | EPHX1 (0.46) | TRPV1TRPM8ALDH1A1HPGDLMNA | |
| SCHEMBL457824 | 0.75 | EPHX1 (0.51) | TRPV1TRPM8KCNA5CYP19A1 | |
| SCHEMBL9951572 | 0.75 | EPHX1 (0.51) | TRPV1TRPM8KCNA5CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111108090-A | Fragrance precursor | 高砂香料工业株式会社 | 2020-05-05 | — | — | CN | disclosed |
| JP-2011105647-A | DENTIFRICE COMPOSITION | LION CORP | 2011-06-02 | — | — | JP | disclosed |