Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889685 | 1.00 | CYP1A2 (0.69) | CYP1A2ALDH1A1HIF1AMAPTMEN1 | |
| SCHEMBL28778368 | 0.89 | MAPK1 (0.58) | CYP1A2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15819946 | 0.87 | CYP1A2 (0.64) | CYP1A2ALDH1A1HIF1AMAPTMEN1 | |
| SCHEMBL1578785 | 0.87 | CYP1A2 (0.64) | CYP1A2ALDH1A1HIF1AMAPTMEN1 | |
| SCHEMBL6037267 | 0.86 | CYP1A2 (0.73) | CYP1A2ALDH1A1MAPTLMNAAMY1A | |
| Hydrochloric Acid SCHEMBL14247410 | 0.85 | CYP1A2 (0.62) | CYP1A2ALDH1A1HIF1AMAPTMEN1 | |
| SCHEMBL6292292 | 0.84 | CYP1A2 (0.75) | CYP1A2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3661590 | 0.83 | CYP1A2 (0.51) | CYP1A2ALDH1A1HIF1AMAPTMEN1 | |
| SCHEMBL6597479 | 0.81 | CYP1A2 (0.47) | CYP1A2ALDH1A1HIF1AMAPTMEN1 | |
| SCHEMBL20731895 | 0.81 | CYP1A2 (0.47) | CYP1A2ALDH1A1HIF1AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248471-B | Preparation method of zolamide drug intermediate and intermediate thereof | 南京桦冠生物技术有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-113248471-A | Preparation method of zolamide drug intermediate and intermediate thereof | 南京桦冠生物技术有限公司 | 2021-08-13 | — | — | CN | claimed |
| US-12187684-B2 | Benzimidazole derivatives as modulators of retinoid-related orphan receptor gamma (RORγ) and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2025-01-07 | — | — | US | disclosed |
| CN-116023321-B | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2024-11-29 | — | — | CN | disclosed |
| WO-2024141128-A4 | STING INHIBITOR PRODRUG AND MEDICAL USE THEREOF | 中国药科大学 | 2024-09-19 | — | — | WO | disclosed |
| CN-114436955-B | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2024-08-09 | — | — | CN | disclosed |
| WO-2024141128-A2 | STING INHIBITOR PRODRUG AND MEDICAL USE THEREOF | 中国药科大学 | 2024-07-04 | — | — | WO | disclosed |
| WO-2024125629-A1 | UREIC COMPOUND AND PHARMACEUTICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2024-06-20 | — | — | WO | disclosed |
| WO-2024067560-A1 | SULFONAMIDE COMPOUND AND MEDICAL USE THEREOF | 中国药科大学 | 2024-04-04 | — | — | WO | disclosed |
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-117682973-A | Sulfonamide compound and medical application thereof | 中国药科大学 | 2024-03-12 | — | — | CN | disclosed |
| EP-1448536-A1 | CYCLOPROPYL-CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6770648-B2 | ANTIDIABETIC AGENTS | TULARIK INC. | 2004-08-03 | — | — | US | disclosed |
| US-6686363-B2 | EFFECTIVE AGAINST MULTI-RESISTANT BACTERIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030225107-A1 | CYCLOPROPYL CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK SHARP & DOHME CORP. | 2003-12-04 | — | — | US | disclosed |
| US-20030139390-A1 | Compounds for the modulation of PPARgamma activity | TULARIK INC. | 2003-07-24 | — | — | US | disclosed |
| WO-2003048136-A1 | CYCLOPROPYL HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-06-12 | — | — | WO | disclosed |
| CN-1368961-A | Compounds that modulate PPAR γ activity | TULARIK INC (US) | 2002-09-11 | — | — | CN | disclosed |
| EP-1192137-A1 | COMPOUNDS FOR THE MODULATION OF PPAR$g(g) ACTIVITY | Tularik Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001000579-A1 | COMPOUNDS FOR THE MODULATION OF PPARη ACTIVITY | TULARIK INC. (US) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139390-A1 | Compounds for the modulation of PPARgamma activity | PPARG, PPARA, PPARD | CYP1A2 910/4885ALDH1A1 1831/4885HIF1A 2857/4885 |
| US-12187684-B2 | Benzimidazole derivatives as modulators of retinoid-related orphan receptor gamma (RORγ) and pharmaceutical use thereof | RORC, RORB, RORA | CYP1A2 295/4885ALDH1A1 244/4885HIF1A 1879/4885 |
| US-20030225107-A1 | CYCLOPROPYL CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | ALAD, OXA1L, ECI1 | CYP1A2 406/4885ALDH1A1 824/4885HIF1A 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.