Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19945786 | 0.77 | RAB9A (0.37) | RAB9ACRHR1 | |
| SCHEMBL20343818 | 0.75 | HPGD (0.39) | RAB9A | |
| SCHEMBL20343740 | 0.73 | SLC26A6 (0.37) | RAB9A | |
| SCHEMBL19945665 | 0.73 | ABCB1 (0.38) | RAB9A | |
| SCHEMBL19945803 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL21319007 | 0.67 | RAB9A (0.31) | RAB9A | |
| SCHEMBL21318994 | 0.67 | TLR7 (0.33) | RAB9A | |
| SCHEMBL19945798 | 0.67 | KCNQ3 (0.32) | — | |
| SCHEMBL19945582 | 0.65 | HTT (0.34) | RAB9A | |
| SCHEMBL21318999 | 0.64 | CHRNA7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776439-B1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-04 | — | — | EP | disclosed |