Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19945786 | 0.74 | RAB9A (0.37) | RAB9ANPC1 | |
| SCHEMBL19945665 | 0.70 | ABCB1 (0.38) | RAB9ANPC1 | |
| SCHEMBL20343740 | 0.70 | SLC26A6 (0.37) | RAB9A | |
| SCHEMBL20343735 | 0.67 | RAB9A (0.32) | RAB9A | |
| SCHEMBL20343818 | 0.67 | HPGD (0.39) | RAB9A | |
| SCHEMBL19945803 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL19945798 | 0.64 | KCNQ3 (0.32) | — | |
| SCHEMBL21319007 | 0.63 | RAB9A (0.31) | TLR7RAB9A | |
| SCHEMBL23019016 | 0.62 | MAP4K4 (0.35) | RAB9A | |
| SCHEMBL21318940 | 0.62 | ADORA3 (0.42) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294740-B1 | NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2019-09-04 | — | — | EP | disclosed |