Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980400 | 0.79 | MPO (0.40) | SLC6A4ALOX5 | |
| SCHEMBL27680111 | 0.76 | ERN1 (0.51) | ESR1CYP19A1ESR2CNR1APLNR | |
| SCHEMBL19980344 | 0.75 | NPY2R (0.40) | — | |
| SCHEMBL18402965 | 0.75 | MTNR1A (0.48) | ESR1CYP19A1ESR2MTNR1AMTNR1B | |
| SCHEMBL23575258 | 0.74 | ESR1 (0.47) | ESR1CYP19A1ESR2APLNRMTNR1A | |
| SCHEMBL30250416 | 0.74 | ESR1 (0.47) | ESR1CYP19A1ESR2APLNRMTNR1A | |
| SCHEMBL9417780 | 0.72 | APLNR (0.58) | CNR1APLNRCNR2 | |
| SCHEMBL16772275 | 0.72 | KMT2A (0.52) | ESR1CYP19A1ESR2APLNR | |
| SCHEMBL5024499 | 0.72 | ESR1 (0.49) | ESR1CYP19A1ESR2POLB | |
| SCHEMBL7632593 | 0.70 | CNR1 (0.39) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342771-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2018-07-04 | — | — | EP | disclosed |