Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 2/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19659016 | 0.83 | CYP3A4 (0.40) | NPY2RCYP3A4CYP2D6CYP2C9LIPG | |
| SCHEMBL2903423 | 0.80 | LIPG (0.48) | NPY2RCYP3A4CYP2D6CYP2C9LIPG | |
| SCHEMBL14840424 | 0.80 | LIPG (0.44) | NPY2RCYP3A4CYP2D6CYP2C9LIPG | |
| SCHEMBL19980400 | 0.78 | MPO (0.40) | CYP3A4CTRC | |
| SCHEMBL14839969 | 0.77 | LIPG (0.46) | NPY2RCYP3A4CYP2D6CYP2C9LIPG | |
| SCHEMBL20344678 | 0.75 | ESR1 (0.38) | — | |
| SCHEMBL3218535 | 0.75 | NPY2R (0.44) | NPY2RLIPGBIDBCL2L1MCL1 | |
| SCHEMBL10988376 | 0.74 | ALDH1A1 (0.48) | CYP3A4THRB | |
| SCHEMBL5223768 | 0.74 | LIPG (0.56) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL5499862 | 0.74 | LIPG (0.56) | LIPGTHRATHRBNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2956452-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2018-03-21 | — | — | EP | disclosed |