Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596389 | 0.81 | MAPT (0.47) | METMAOAMAOBALDH1A1KDM4E | |
| SCHEMBL22210774 | 0.80 | ALDH1A1 (0.47) | METLMNAALDH1A1KDM4EBRD4 | |
| SCHEMBL12848314 | 0.80 | ALDH1A1 (0.43) | LMNAMAOAMAOBALDH1A1PKM | |
| SCHEMBL11633601 | 0.77 | ALDH1A1 (0.46) | METALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL22210780 | 0.74 | NPC1 (0.58) | METLMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL12376651 | 0.71 | BRD4 (0.73) | LMNAALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL9004445 | 0.71 | MET (0.53) | METMEN1KMT2A | |
| SCHEMBL23940153 | 0.71 | ALDH1A1 (0.50) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL550463 | 0.70 | ALDH1A1 (0.56) | LMNAALDH1A1PKMKDM4EHTT | |
| SCHEMBL13145677 | 0.69 | LMNA (0.48) | LMNAMAOAMAOBALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239147-B1 | QUINOLINE DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2019-08-28 | — | — | EP | disclosed |
| EP-3067356-B1 | PYRROLO PYRIMIDINE DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2018-07-04 | — | — | EP | disclosed |