Sugi Predict

Sugi Predict / Compounds / SCHEMBL550463

SCHEMBL550463

SCHEMBL550463

CC(C)NC(=O)c1ccccc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.56
▸ ALOX15 P16050 1/20 0.56
▸ KDM4E B2RXH2 5/20 0.53
▸ HTT P42858 1/20 0.53
▸ KMT2A Q03164 4/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ POLB P06746 1/20 0.51
▸ HPGD P15428 3/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ APEX1 P27695 1/20 0.50
▸ PKM P14618 1/20 0.50
▸ TAAR1 Q96RJ0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14015339 0.86 ALDH1A1 (0.54) ALDH1A1ALOX15KDM4EHTTKMT2A
SCHEMBL12170872 0.85 ALDH1A1 (0.52) ALDH1A1ALOX15KDM4EHTTKMT2A
SCHEMBL7150322 0.85 ALDH1A1 (0.52) ALDH1A1ALOX15KDM4EHTTKMT2A
SCHEMBL13544849 0.84 LMNA (0.51) ALDH1A1KDM4EHTTKMT2AMEN1
SCHEMBL1285890 0.83 ALDH1A1 (0.73) ALDH1A1KDM4EKMT2APOLBHPGD
SCHEMBL743064 0.83 ALDH1A1 (0.73) ALDH1A1KDM4EKMT2APOLBHPGD
SCHEMBL1285869 0.83 ALDH1A1 (0.73) ALDH1A1KDM4EKMT2APOLBHPGD
SCHEMBL799662 0.83 KMT2A (0.75) ALDH1A1ALOX15KDM4EHTTKMT2A
SCHEMBL8655185 0.83 KMT2A (0.48) ALDH1A1ALOX15KDM4EKMT2AMEN1
SCHEMBL5674044 0.82 IRAK4 (0.53) ALDH1A1KDM4EHTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114086407-A Novel environment-friendly color modifier and preparation method thereof 浙江汉邦新材料股份有限公司 2022-02-25 — — CN claimed
EP-3551633-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 — — EP claimed
WO-2018108230-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 — — WO claimed
EP-3377492-B1 CATALYST FOR THE PREPARATION OF POLYURETHANES BASF SE (DE) 2022-08-31 — — EP disclosed
CN-108368109-B Catalyst for preparing polyurethane 巴斯夫欧洲公司 2021-11-23 — — CN disclosed
US-11021560-B2 Catalyst for the preparation of polyurethanes BASF SE (DE) 2021-06-01 — — US disclosed
US-11021560-B2 Catalyst for the preparation of polyurethanes BASF SE (DE) 2021-06-01 — — US disclosed
US-20200172652-A9 CATALYST FOR THE PREPARATION OF POLYURETHANES BASF SE (DE) 2020-06-04 — — US disclosed
US-20200172652-A9 CATALYST FOR THE PREPARATION OF POLYURETHANES BASF SE (DE) 2020-06-04 — — US disclosed
US-10570269-B2 Composition containing microparticles TOKYO OHKA KOGYO CO., LTD. (JP) 2020-02-25 — — US disclosed
US-20180327534-A1 CATALYST FOR THE PREPARATION OF POLYURETHANES BASF SE (CH) 2018-11-15 — — US disclosed
CN-1759105-A Phthalamide derivatives having insecticidal activity BAYER CROPSCIENCE AG (DE) 2006-04-12 — — CN disclosed
EP-1606271-A1 INSECTICIDAL PHTHALAMIDE DERIVATIVES Bayer CropScience AG (DE) 2005-12-21 — — EP disclosed
EP-1226113-B1 ESTERS COMPRISING A SECONDARY CARBAMOYL FUNCTION AND THEIR USE AS ODORANT ALCOHOL PRECURSORS FIRMENICH & CIE (CH) 2005-11-09 — — EP disclosed
WO-2005095351-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2005-10-13 — — WO disclosed
WO-2004080984-A1 INSECTICIDAL PHTHALAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2004-09-23 — — WO disclosed
US-6677297-B2 PERFUMES FOR TEXTILES; PROLONGED DIFFUSION FIRMENICH SA (CH) 2004-01-13 — — US disclosed
US-20020144360-A1 Esters comprising a secondary carbamoyl function and their use as odorant alcohol precursors FIRMENICH SA (CH) 2002-10-10 — — US disclosed
EP-1226113-A1 ESTERS COMPRISING A SECONDARY CARBAMOYL FUNCTION AND THEIR USE AS ODORANT ALCOHOL PRECURSORS Firmenich S.A. (CH) 2002-07-31 — — EP disclosed
WO-2001028980-A1 ESTERS COMPRISING A SECONDARY CARBAMOYL FUNCTION AND THEIR USE AS ODORANT ALCOHOL PRECURSORS FIRMENICH S.A. (CH) 2001-04-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180327534-A1 CATALYST FOR THE PREPARATION OF POLYURETHANES PUF60, UNG, UMPS ALDH1A1 972/4885ALOX15 1694/4885KDM4E 1421/4885
US-20200172652-A9 CATALYST FOR THE PREPARATION OF POLYURETHANES PUF60, UNG, UMPS ALDH1A1 972/4885ALOX15 1694/4885KDM4E 1421/4885
US-11021560-B2 Catalyst for the preparation of polyurethanes PUF60, UNG, UMPS ALDH1A1 972/4885ALOX15 1694/4885KDM4E 1421/4885
US-10570269-B2 Composition containing microparticles CHMP4B, EXOSC10, EXOSC9 ALDH1A1 1737/4885ALOX15 2356/4885KDM4E 3300/4885
US-20020144360-A1 Esters comprising a secondary carbamoyl function and their use as odorant alcohol precursors ADH1C, ADH1A, CBR1 ALDH1A1 72/4885ALOX15 630/4885KDM4E 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.